User profiles for Anand Mehta

Anand S Mehta

SmartState Endowed Chair of Proteomic Biomarkers and Professor, Department of Cell and …
Verified email at musc.edu
Cited by 10859

Molecular viral oncology of hepatocellular carcinoma

TM Block, AS Mehta, CJ Fimmel, R Jordan - Oncogene, 2003 - nature.com
Hepatocellular carcinoma (HCC) is the fifth most common cancer, but the third leading cause
of cancer death, in the world, with more than 500 000 fatalities annually. The major etiology …

Use of targeted glycoproteomics to identify serum glycoproteins that correlate with liver cancer in woodchucks and humans

…, RA Dwek, TS Mattu, AS Mehta - Proceedings of the …, 2005 - National Acad Sciences
Chronic infection with hepatitis B virus (HBV) is associated with the majority of hepatocellular
carcinoma (HCC). The diagnosis of HCC is usually made in the late stages of the disease, …

GP73, a resident Golgi glycoprotein, is a novel serum marker for hepatocellular carcinoma

…, PR Romano, O Nikolaeva, L Steel, A Mehta… - Journal of …, 2005 - Elsevier
BACKGROUND/AIMS: Golgi protein-73 (GP73) is up-regulated in hepatocellular carcinoma
(HCC). The aims of this study were to determine if GP73 is detected in the serum, and to …

Imino sugars inhibit the formation and secretion of bovine viral diarrhea virus, a pestivirus model of hepatitis C virus: implications for the development of broad …

N Zitzmann, AS Mehta, S Carrouée… - Proceedings of the …, 1999 - National Acad Sciences
One function of N-linked glycans is to assist in the folding of glycoproteins by mediating
interactions of the lectin-like chaperone proteins calnexin and calreticulin with nascent …

[HTML][HTML] α-Glucosidase inhibitors as potential broad based anti-viral agents

A Mehta, N Zitzmann, PM Rudd, TM Block, RA Dwek - FEBS letters, 1998 - Elsevier
N-Linked oligosaccharides play many roles in the fate and functions of glycoproteins. One
function is to assist in the folding of proteins by mediating interactions of the lectin-like …

Human immunodeficiency virus-related microbial translocation and progression of hepatitis C

…, TM Block, A Mehta, R Long, GD Kirk, SH Mehta… - Gastroenterology, 2008 - Elsevier
Background & Aims: Human immunodeficiency virus (HIV)-1 infection has been associated
with enhanced microbial translocation, and microbial translocation is a mechanism through …

[HTML][HTML] Lectin capture strategies combined with mass spectrometry for the discovery of serum glycoprotein biomarkers

…, G Malik, J Diaz, T Block, A Mehta… - Molecular & Cellular …, 2006 - ASBMB
The application of mass spectrometry to identify disease biomarkers in clinical fluids like
serum using high throughput protein expression profiling continues to evolve as technology …

Proteomic analysis of serum associated fucosylated glycoproteins in the development of primary hepatocellular carcinoma

…, HWL Hann, TM Block, AS Mehta - Journal of proteome …, 2006 - ACS Publications
Changes in N-linked glycosylation are known to occur during the development of cancer.
For example, increased branching of oligosaccharides has been associated with metastasis …

[HTML][HTML] MALDI imaging mass spectrometry profiling of N-glycans in formalin-fixed paraffin embedded clinical tissue blocks and tissue microarrays

…, BA Neely, Y Shao, H Tang, DA Troyer, AS Mehta… - PloS one, 2014 - journals.plos.org
A recently developed matrix-assisted laser desorption/ionization imaging mass spectrometry
(MALDI-IMS) method to spatially profile the location and distribution of multiple N-linked …

Novel fucosylated biomarkers for the early detection of hepatocellular carcinoma

…, J Marrero, AM Di Bisceglie, TM Block, AS Mehta - … Biomarkers & Prevention, 2009 - AACR
Abstract Changes in glycosylation, most notably fucosylation, have been associated with
the development of hepatocellular carcinoma (HCC). In this report, the levels of fucosylated …