User profiles for Andrew Wragg

Andrew Wragg

Barts Heart Centre
Verified email at bartshealth.nhs.uk
Cited by 10743

p53 regulates mitochondrial respiration

S Matoba, JG Kang, WD Patino, A Wragg, M Boehm… - Science, 2006 - science.org
The energy that sustains cancer cells is derived preferentially from glycolysis. This metabolic
change, the Warburg effect, was one of the first alterations in cancer cells recognized as …

A rapid protocol for the prevention of contrast-induced renal dysfunction: the RAPPID study

CSR Baker, A Wragg, S Kumar, R De Palma… - Journal of the American …, 2003 - jacc.org
Objectives : This study was designed to test a rapid protocol of intravenous acetylcysteine for
prevention of radiocontrast-induced nephropathy (RCIN). Background : Oral acetylcysteine (…

TGF-β signaling mediates endothelial-to-mesenchymal transition (EndMT) during vein graft remodeling

…, B Taylor, JD Lanzer, A Wragg… - Science translational …, 2014 - science.org
Veins grafted into an arterial environment undergo a complex vascular remodeling process.
Pathologic vascular remodeling often results in stenosed or occluded conduit grafts. …

Implementing workplace‐based assessment across the medical specialties in the United Kingdom

JR Wilkinson, JGM Crossley, A Wragg, P Mills… - Medical …, 2008 - Wiley Online Library
Objectives To evaluate the reliability and feasibility of assessing the performance of medical
specialist registrars (SpRs) using three methods: the mini‐clinical evaluation exercise (mini‐…

Successful recanalization of chronic total occlusions is associated with improved long-term survival

…, CA Thompson, A Mathur, A Wragg… - JACC: Cardiovascular …, 2012 - jacc.org
Objectives : This study investigated the impact of procedural success on mortality following
chronic total occlusion (CTO) percutaneous coronary intervention (PCI) in a large cohort of …

[HTML][HTML] A prospective international multicentre cohort study of intraoperative heart rate and systolic blood pressure and myocardial injury after noncardiac surgery …

…, T Ahmad, E Niebrzegowska, A Wragg… - Anesthesia & …, 2018 - journals.lww.com
BACKGROUND: The association between intraoperative cardiovascular changes and
perioperative myocardial injury has chiefly focused on hypotension during noncardiac surgery. …

Acute myocarditis presenting as acute coronary syndrome: role of early cardiac magnetic resonance in its diagnosis

…, A Deaner, M Sheaf, S Baithun, S Petersen, A Wragg… - Heart, 2011 - heart.bmj.com
Background In patients presenting with acute cardiac symptoms, abnormal ECG and raised
troponin, myocarditis may be suspected after normal angiography. Aims To analyse cardiac …

Diagnostic performance of hyperaemic myocardial blood flow index obtained by dynamic computed tomography: does it predict functionally significant coronary …

A Rossi, A Dharampal, A Wragg… - European Heart …, 2014 - academic.oup.com
Aims The severity of coronary artery narrowing is a poor predictor of functional significance,
in particular in intermediate coronary lesions (30–70% diameter narrowing). The aim of this …

Integrating CT myocardial perfusion and CT-FFR in the work-up of coronary artery disease

…, RG Chelu, S Segreto, ML Dijkshoorn, A Wragg… - JACC: Cardiovascular …, 2017 - jacc.org
Objectives : The aim of this study was to investigate the individual and combined accuracy
of dynamic computed tomography (CT) myocardial perfusion imaging (MPI) and computed …

The use of novel oral anticoagulants compared to vitamin K antagonists (warfarin) in patients with left ventricular thrombus after acute myocardial infarction

…, A Timmis, A Baumbach, A Wragg… - European Heart …, 2021 - academic.oup.com
Aim Current guidelines recommend the use of vitamin K antagonist (VKA) for up to 3–6
months for treatment of left ventricular (LV) thrombus post-acute myocardial infarction (AMI). …