IL-17 is a cytokine produced by T cells in response to IL-23. Recent data support a new
subset of CD4 Th cells distinct from Th1 or Th2 cells that produce IL-17 and may contribute to …

The transcription factors that regulate differentiation into the monocyte subset in bone
marrow have not yet been identified. Here we found that the orphan nuclear receptor NR4A1 …

We report a genome-wide association (GWA) study of severe malaria in The Gambia. The
initial GWA scan included 2,500 children genotyped on the Affymetrix 500K GeneChip, and a …

PURPOSE: To describe social support for weight loss shared by members of a large Internet
weight loss community. METHODS: We conducted a mixed-methods study with surveys (n=…

IFN-γ is necessary in both humans and mice for control of Mycobacterium tuberculosis. CD4
T cells are a significant source of IFN-γ during acute infection in mice and are required for …

The British Thoracic Society (BTS) Home Oxygen Guideline provides detailed evidence-based
guidance for the use of home oxygen for patients out of hospital. Although the majority of …

The liver is an important site of host-microbe interaction. Although hepatocytes have been
reported to be responsive to lipopolysaccharide (LPS), the global gene expression changes …

Dengue is a major public health issue in tropical and subtropical regions worldwide. The
four serotypes of dengue virus (DENV1–DENV4) are spread primarily by Aedes aegypti and …

A global pandemic of a new highly contagious disease called COVID-19 resulting from
coronavirus (severe acute respiratory syndrome (SARS)-Cov-2) infection was declared in …

As part of a systemic assessment toward social sustainability of egg production, we have
reviewed current knowledge about the environmental impacts of egg production systems and …