BACKGROUND Circulating biomarkers, such as circulating tumor cells (CTCs) and circulating
tumor DNA (ctDNA), are both considered for blood-based mutation detection, but limited …

Background Nrf2 regulates cellular antioxidant defence in lung cells, including epithelial
cells and alveolar macrophages (AM). The Nrf2/Keap-1 pathway can be modulated by …

Although the pathogenesis of idiopathic pulmonary fibrosis (IPF) remains elusive (1), one of
the most intriguing aspects concerns the possible role of mucins. A strong association has …

Lung macrophage iron levels are increased in COPD patients. Lung macrophage iron levels
are thought to be increased by cigarette smoke, but the role of red blood cells (RBCs) as a …

COVID-19 is the infectious disease caused by the recently discovered coronavirus, SARS-CoV-2,
unknown before the outbreak in Wuhan, China, in December 2019. COVID-19 is a …

Pleural epithelioid hemangioendothelioma is a really rare tumor of vascular origin and
potentially aggressive behavior. We report the case of an 85 years old male patient diagnosed of …

Mesothelioma is classified into three histological subtypes, epithelioid, sarcomatoid, and
biphasic, according to the relative proportions of epithelioid and sarcomatoid tumor cells present…

Malignant Mesothelioma is a difficult to diagnose and highly lethal cancer usually associated
with asbestos exposure. It can be broadly classified into three subtypes: Epithelioid, …

Background Routine clinical application of circulating tumour cells (CTCs) for blood based
diagnostics is yet to be established. Despite growing evidence of their clinical utility for …

This study aimed to molecularly characterise colorectal pulmonary metastases (PM) and
investigate whether their molecular profiles were concordant with those of the primary tumour. …