Although exacerbations of chronic obstructive pulmonary disease (COPD) are associated
with symptomatic and physiological deterioration, little is known of the time course and …

The effects of respiratory viral infection on the time course of chronic obstructive pulmonary
disease (COPD) exacerbation were examined by monitoring changes in systemic …

BACKGROUND Although it is presumed that exacerbations of chronic obstructive
pulmonary disease (COPD) are associated with increased airway inflammation, there is little …

Study objectives Patients with COPD experience lower airway and systemic inflammation,
and an accelerated decline in FEV 1 . There is no evidence on whether this inflammation …

Respiratory tract infections may acutely increase risk from coronary heart disease (CHD),
though the mechanisms have not been defined. Patients with chronic obstructive pulmonary …

Background Patients with chronic obstructive pulmonary disease (COPD) often have vitamin
D deficiency, which is associated with increased susceptibility to upper respiratory infection…

Rationale Asthma exacerbations are commonly precipitated by viral upper respiratory
infections (URIs). Vitamin D insufficiency associates with susceptibility to URI in patients with …

Rationale: Low uptake of low-dose computed tomography (LDCT) lung cancer screening,
particularly by current smokers of a low socioeconomic position, compromises effectiveness …

Patients with COPD usually experience mucus hypersecretion as a result of airway inflammation
and response to noxious stimuli. These in turn lead to worsening airway resistance, …

Rationale: Individuals eligible for lung cancer screening (LCS) by low-dose computed
tomography (LDCT) are also at risk of chronic obstructive pulmonary disease (COPD) due to age …