Objective To develop simple, practical criteria for clinical diagnosis of fibromyalgia that are
suitable for use in primary and specialty care and that do not require a tender point …

Background Effective new therapies are needed for rheumatoid arthritis. Current therapies
target the products of activated macrophages; however, T cells also have an important role in …

Objectives The provisional criteria of the American College of Rheumatology (ACR) 2010
and the 2011 self-report modification for survey and clinical research are widely used for …

The minor spliceosome is a ribonucleoprotein complex that catalyses the removal of an
atypical class of spliceosomal introns (U12-type) from eukaryotic messenger RNAs 1 , 2 . It was …

ContextCarcinoma of the esophagus traditionally has been treated by surgery or radiation
therapy (RT), but 5-year overall survival rates have been only 5% to 10%. We previously …

Objective. To develop a fibromyalgia (FM) survey questionnaire for epidemiologic and clinical
studies using a modification of the 2010 American College of Rheumatology Preliminary …

Background: The selective co-stimulation modulator abatacept demonstrated efficacy for
treating rheumatoid arthritis in early clinical studies. Objective: To evaluate the effects of …

In most species the length of a pregnancy exceeds that of the luteal phase of the ovarian
cycle. The conceptus within the uterus, therefore, is believed to produce a substance or …

In eukaryotes, dozens of posttranscriptional modifications are directed to specific nucleotides
in ribosomal RNAs (rRNAs) by small nucleolar RNAs (snoRNAs). We identified homologs …

Successful outcome of human pregnancy not only impacts the quality of infant life and well-being,
but considerable evidence now suggests that what happens during fetal development …