Neuroendocrine neoplasms (NENs) are a heterogeneous group of neoplasms ranging from
well-differentiated, slowly growing tumors to poorly differentiated carcinomas. These tumors …

Small-bowel tumors represent a rare entity comprising 0.6% of all new cancer cases in the
US, and only 3% of all gastrointestinal neoplasms. They are a heterogenous group of …

Background & Aims Antivirals represent the mainstay of chronic hepatitis B treatment given
their efficacy and tolerability, but rates of functional cure remain low during long-term therapy. …

Chronic hepatitis B (CHB) remains a global healthcare burden. Although the recent developments
in the field have led to a reduction in incidence, the morbidity and mortality including …

In spite of a decrease in the prevalence and incidence seen in recent years, chronic hepatitis
B (CHB) still remains a major healthcare challenge, prevalent mostly in developing but also …

Hepatitis B virus reactivation (HBVr) is emerging as an important clinical entity, with the
advent of highly potent immunosuppression licensed for use as the treatment of a widening …

Objectives Vasoactive intestinal peptide–secreting tumors (VIPomas) are rare functioning
neuroendocrine tumors often characterized by a difficult-to-control secretory syndrome and …

The importance of epigenetic changes in the development of hepatic steatosis is largely
unknown. The histone variant macroH2A1 under alternative splicing gives rise to macroH2A1.1 …

Colon screening programs have reduced colon cancer mortality. Population screening should
be minimally invasive, safe, acceptably sensitive, cost-effective, and scalable. The range …

Opinion statement Gastroenteropancreatic neuroendocrine neoplasms (GEP NENs) comprise
a heterogeneous group of slow growing tumors arising from the neuroendocrine cells of …