Inherited thrombocytopenias are a heterogeneous group of disorders characterized by
abnormally low platelet counts which can be associated with abnormal bleeding. Next-generation …

Purpose The incidence of invasive fungal disease (IFD) is rising, but its treatment in paediatric
haematology and oncology patients is not yet standardised. This review aimed to critically …

Methodology This guideline was compiled according to the British Society for Haematology (BSH)
process at (http://www.bcshguidelines.com). The Grading of Recommendations …

Stem cell transplant (SCT) outcomes in high-risk and relapsed/refractory (R/R) pediatric acute
myeloid leukemia (AML) and myelodysplastic syndrome (MDS) have been historically poor…

Unlike older children with acute lymphoblastic leukemia (ALL), there has been almost no
improvement in outcome for infants in the last 2 decades. Six-year event-free survival (EFS) …

Patients with an ABL‐class fusion have a high risk of relapse on standard chemotherapy but
are sensitive to tyrosine kinase inhibitors (TKI). In UKALL2011, we screened patients with …

Terminal complement blockade by humanised monoclonal antibody eculizumab has been
used to treat transplantation-associated thrombotic microangiopathy (TA-TMA) in recent years…

In January 2020, a novel coronavirus was sequenced in China (SARS-CoV-2) and it was
linked to cases of severe acute respiratory syndrome as part of a new disease which was …

Haematopoietic stem cell transplantation (HSCT) remains the only curative option in Fanconi
anaemia (FA). We analysed the outcome of children transplanted for FA between 1999 and …

Background Lymphoproliferation and autoimmune cytopenias characterise autoimmune
lymphoproliferative syndrome. Other conditions sharing these manifestations have been termed …