Purpose: To determine whether -interferon is effective in terminating viral replication and in
eradicating the carrier state in patients with chronic hepatitis B virus (HBV) infection. Data …

Objective.—Laboratory utilization has steadily increased, and some studies suggest
inappropriate utilization. Therefore, we wished to assess studies that measure inappropriate …

Meta-analytic methods were applied to review clinical trials published in English that have
assessed the efficacy of parenteral nutrition for cirrhotic patients with acute hepatic …

Clinical experience provides clinicians with an intuitive sense of which findings on history,
physical examination, and investigation are critical in making an accurate diagnosis, or an …

This series provides clinicians with strategies and tools to interpret and integrate evidence
from published research in their care of patients. The 2 key principles for applying all the …

Background Universal health care systems seek to ensure access to care on the basis of
need rather than income and to improve the health status of all citizens. We examined the …

Meta-analysis is a method of synthesizing evidence from multiple sources. It has been
increasingly applied to combine results from randomized trials of therapeutic strategies. …

OBJECTIVE: Our purpose was to assess maternal-fetal outcomes in patients with increasing
carbohydrate intolerance not meeting the current criteria for the diagnosis of gestational …

Background In the past decade, the radial artery has frequently been used for coronary
bypass surgery despite concern regarding the possibility of graft spasm. Graft patency is a key …

Background A multicenter population-based study was conducted to develop and validate a
risk index for mortality, intensive care unit (ICU) length of stay, and postoperative length of …