Abnormal bacterial colonisation of the genital tract and subsequent preterm delivery and late miscarriage

…, RF Lamont, D Taylor-Robinson, DJ Morgan, C Ison… - Bmj, 1994 - bmj.com
Objective : To find out whether women with bacterial vaginosis detected early in pregnancy
are at increased risk of preterm delivery. Design : Prospective description cohort study. …

[HTML][HTML] Prevalence, risk factors, and uptake of interventions for sexually transmitted infections in Britain: findings from the National Surveys of Sexual Attitudes and …

…, B Erens, P Prah, W Macdowall, K Wellings, CA Ison… - The Lancet, 2013 - thelancet.com
Background Population-based estimates of prevalence, risk distribution, and intervention
uptake inform delivery of control programmes for sexually transmitted infections (STIs). We …

Rapid sequence-based identification of gonococcal transmission clusters in a large metropolitan area

IMC Martin, CA Ison, DM Aanensen… - The Journal of …, 2004 - academic.oup.com
In large metropolitan areas, which typically have the highest rates of gonorrhea, the identification
of chains of transmission by use of partner notification is problematic, and there is an …

High-Level Azithromycin Resistance Occurs in Neisseria gonorrhoeae as a Result of a Single Point Mutation in the 23S rRNA Genes

SA Chisholm, J Dave, CA Ison - Antimicrobial agents and …, 2010 - Am Soc Microbiol
High-level azithromycin resistance (AZM-HR), defined as a MIC of ≥256 mg/liter, emerged
in Neisseria gonorrhoeae in the United Kingdom in 2004. To determine the mechanism of …

Epidemiology of Mycoplasma genitalium in British men and women aged 16–44 years: evidence from the third National Survey of Sexual Attitudes and …

P Sonnenberg, CA Ison, S Clifton… - International Journal …, 2015 - academic.oup.com
Background: There are currently no large general population epidemiological studies of
Mycoplasma genitalium (MG), which include prevalence, risk factors, symptoms and co-infection …

Cephalosporin MIC creep among gonococci: time for a pharmacodynamic rethink?

…, DA Lewis, T Nichols, CA Ison… - Journal of …, 2010 - academic.oup.com
Background Gonorrhoea has been among the easiest infections to cure with antibiotics.
Nevertheless, emerging resistance has driven repeated treatment shifts. Decreased …

[PDF][PDF] Laboratory diagnosis of sexually transmitted infections, including human immunodeficiency virus

M Unemo, R Ballard, C Ison, D Lewis, F Ndowa… - 2013 - apps.who.int
Sexually transmitted infections (STIs), including those caused by the human immunodeficiency
virus (HIV) types 1 and 2, remain an important focus area for global public health. This is …

Lymphogranuloma venereum in the United Kingdom

…, K Fenton, P French, G Dean, C Ison - Clinical infectious …, 2007 - academic.oup.com
Background . Over the past 2 years, lymphogranuloma venereum (LGV), caused by L serovars
of Chlamydia trachomatis, has emerged as a significant problem among men who have …

[HTML][HTML] Decreased susceptibility to cephalosporins among gonococci: data from the Gonococcal Resistance to Antimicrobials Surveillance Programme (GRASP) in …

CA Ison, K Town, C Obi, S Chisholm… - The Lancet Infectious …, 2013 - thelancet.com
Background Effective treatment of gonorrhoea is fundamental to public health control;
however, the ability of Neisseria gonorrhoeae to successively develop resistance to different …

Whole-genome sequences of Chlamydia trachomatis directly from clinical samples without culture

…, C O'Neill, S Parmar, R Pitt, S Baker, CA Ison… - Genome …, 2013 - genome.cshlp.org
The use of whole-genome sequencing as a tool for the study of infectious bacteria is of growing
clinical interest. Chlamydia trachomatis is responsible for sexually transmitted infections …