Cytotoxic therapies, besides directly inducing cancer cell death, can stimulate immune-dependent
tumor growth control or paradoxically accelerate tumor progression. The underlying …

The centrosome is essential for cytotoxic T lymphocyte (CTL) function, contacting the plasma
membrane and directing cytotoxic granules for secretion at the immunological synapse. …

This study characterized the acoustic properties of an International Electromechanical
Commission (IEC) agar-based tissue mimicking material (TMM) at ultrasound frequencies in the …

Melanoma is a clinically heterogeneous disease, and current strategies for treatment of the
primary tumour are based on pathological criteria alone. In the recent past, several DNA‐…

Ultraviolet radiation (UVR) damages the dermis and fibroblasts; and increases melanoma
incidence. Fibroblasts and their matrix contribute to cancer, so we studied how UVR modifies …

Methods We designed a comprehensive data analysis tool to analyse the performance of
our discharge summaries. We presented at clinical governance sessions and arranged …

Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) is a tumor suppressor
and bi-functional lipid and protein phosphatase. We report that the metabolic regulator …

Purpose: Cancer susceptibility and mortality are higher in males, and the mutational and
transcriptomic landscape of cancer differs by sex. The current assumption is that men are at …

Aims and methodAdmissions of patients to secure forensic hospitals are often lengthy.
Previous research has examined factors associated with prolonged admission, but studies …

An audit of fifty patients receiving Artiss™ fibrin sealant in lateral selective neck dissections
Artiss™ is a fibrin sealant used in wound closure of lateral selective neck dissections. The …