[HTML][HTML] Multiomic analysis of malignant pleural mesothelioma identifies molecular axes and specialized tumor profiles driving intertumor heterogeneity

…, C Girard, V Hofman, P Hofman, J Mouroux, C Cohen… - Nature Genetics, 2023 - nature.com
Malignant pleural mesothelioma (MPM) is an aggressive cancer with rising incidence and
challenging clinical management. Through a large series of whole-genome sequencing data, …

Self-expanding covered metallic stent as a bridge to surgery in esophageal cancer: impact on oncologic outcomes

…, A Ayav, L Brunaud, L Bresler, C Cohen… - Journal of the American …, 2015 - Elsevier
Background Self-expanding metallic stents (SEMSs) have been used as a bridge to surgery,
relieving dysphagia and maintaining nutrition, in patients with operable but obstructive …

[HTML][HTML] Current views on tumor mutational burden in patients with non-small cell lung cancer treated by immune checkpoint inhibitors

…, S Lalvée, O Bordone, C Cohen… - Journal of thoracic …, 2019 - ncbi.nlm.nih.gov
In the last few years, the treatment of patients with non-small cell lung cancer (NSCLC) has
impressively benefitted from immunotherapy, in particular from the inhibition of immune …

[HTML][HTML] Role of neoadjuvant treatment in clinical T2N0M0 oesophageal cancer: results from a retrospective multi-center European study

…, A Ayav, L Brunaud, L Bresler, C Cohen… - European Journal of …, 2016 - Elsevier
Aims The aims of this study were to compare short- and long-term outcomes for clinical T2N0
oesophageal cancer with analysis of (i) primary surgery (S) versus neoadjuvant therapy …

Effect of mutant variants of the KRAS gene on PD-L1 expression and on the immune microenvironment and association with clinical outcome in lung adenocarcinoma …

…, C Bence, K Zahaf, S Leroy, CH Marquette, C Cohen… - Lung Cancer, 2018 - Elsevier
Objectives The effect of anti-PD-1/PD-L1 inhibitors on lung adenocarcinomas (LADCs) with
KRAS mutations is debatable. We examined the association between specific mutant KRAS …

[HTML][HTML] Optimization of EGFR mutation detection by the fully-automated qPCR-based Idylla system on tumor tissue from patients with non-small cell lung cancer

…, O Bordone, V Lespinet, S Leroy, C Cohen… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Abstract Treatment with EGFR inhibitors is limited to patients with advanced/metastatic non-small
cell lung cancer who have known EGFR mutations. Currently, patient care has to …

Salvage surgery for esophageal cancer: how to improve outcomes?

C Cohen, W Tessier, C Gronnier, F Renaud… - Annals of surgical …, 2018 - Springer
Background Locoregional recurrence rates after definitive chemoradiotherapy (dCRT) for
locally advanced esophageal cancer (EC) are high. Salvage surgery (SALV) is considered the …

Circulating tumour cells as a potential screening tool for lung cancer (the AIR study): protocol of a prospective multicentre cohort study in France

…, J Cadranel, J Mazières, V Jounieaux, C Cohen… - BMJ open, 2017 - bmjopen.bmj.com
Introduction Lung cancer (LC) is the leading cause of death from cancer. Early diagnosis of
LC is of paramount importance in terms of prognosis. The health authorities of most countries …

Lack of correlation between MET and PD-L1 expression in non-small cell lung cancer revealed by comparative study of matched biopsies and surgical resection …

…, O Bordone, V Tanga, A Gómez-Caro, C Cohen… - Lung Cancer, 2023 - Elsevier
Introduction Both MET expression and the PD-L1 tumor proportion score (TPS) are companion
diagnostics for treatment of advanced non-small cell lung carcinoma (aNSCLC) patients. …

Sexual trauma associated with fisting and recreational drugs

CE Cohen, A Giles, M Nelson - Sexually Transmitted Infections, 2004 - sti.bmj.com
There is a rising trend in high risk sexual behaviour among men who have sex with men (MSM),
with concomitant use of recreational drugs. Activities include fisting and unprotected …