Background Patients with cancer are purported to have poor COVID-19 outcomes. However,
cancer is a heterogeneous group of diseases, encompassing a spectrum of tumour …

The diagnosed incidence of small intestine neuroendocrine tumors (SI-NETs) is increasing,
and the underlying genomic mechanisms have not yet been defined. Using exome- and …

Background: Highly active antiretroviral therapy (HAART) has reduced the incidence and
improved the survival of patients with Kaposi sarcoma and AIDS-related non-Hodgkin …

Importance The utility of buccal cells as an epithelial source tissue for epigenome-wide
association studies (EWASs) remains to be demonstrated. Given the direct exposure of buccal …

The molecular alterations that occur in cells before cancer is manifest are largely uncharted.
Lung carcinoma in situ (CIS) lesions are the pre-invasive precursor to squamous cell …

Purpose: Small intestinal neuroendocrine tumors (SINET) are the commonest malignancy of
the small intestine; however, underlying pathogenic mechanisms remain poorly …

BACKGROUND & AIMS: According to the somatic mutation theory, monoclonal colorectal
lesions arise from sequential mutations in the progeny of a single stem cell. However, studies …

The integration of genomic and epigenomic data is an increasingly popular approach for
studying the complex mechanisms driving cancer development. We have developed a method …

Background Human papillomavirus-positive (HPV+) head and neck squamous cell carcinoma
(HNSCC) represents a distinct clinical and epidemiological condition compared with HPV-…

Importance Large cohorts of patients with active cancers and COVID-19 infection are needed
to provide evidence of the association of recent cancer treatment and cancer type with …