User profiles for Claire Waddington

Claire Waddington

University of Cambridge
Verified email at doctors.org.uk
Cited by 8298

Susceptibility to SARS-CoV-2 infection among children and adolescents compared with adults: a systematic review and meta-analysis

…, J Ward, L Hudson, C Waddington… - JAMA …, 2021 - jamanetwork.com
Importance The degree to which children and adolescents are infected by and transmit severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is unclear. The role of children …

Do school closures and school reopenings affect community transmission of COVID-19? A systematic review of observational studies

…, S Russell, JM Birch, JL Ward, C Waddington… - BMJ open, 2021 - bmjopen.bmj.com
Objectives To systematically reivew the observational evidence of the effect of school
closures and school reopenings on SARS-CoV-2 community transmission. Setting Schools (…

An Outpatient, Ambulant-Design, Controlled Human Infection Model Using Escalating Doses of Salmonella Typhi Challenge Delivered in Sodium Bicarbonate …

CS Waddington, TC Darton, C Jones… - Clinical Infectious …, 2014 - academic.oup.com
Background. Typhoid fever is a major global health problem, the control of which is hindered
by lack of a suitable animal model in which to study Salmonella Typhi infection. Until 1974, …

Safety and immunogenicity of AS03B adjuvanted split virion versus non-adjuvanted whole virion H1N1 influenza vaccine in UK children aged 6 months-12 years …

CS Waddington, WT Walker, C Oeser, A Reiner, T John… - Bmj, 2010 - bmj.com
Objectives To compare the safety, reactogenicity, and immunogenicity of an adjuvanted split
virion H1N1 vaccine and a non-adjuvanted whole virion vaccine used in the pandemic …

[HTML][HTML] Transmission of SARS-CoV-2 by children and young people in households and schools: a meta-analysis of population-based and contact-tracing studies

R Viner, C Waddington, O Mytton, R Booy, J Cruz… - Journal of Infection, 2022 - Elsevier
Background The role of children and young people (CYP) in transmission of SARS-CoV-2
in household and educational settings remains unclear. We undertook a systematic review …

Use of cidofovir in a patient with severe mpox and uncontrolled HIV infection

…, K Sun, EP Davies, CS Waddington… - The Lancet Infectious …, 2023 - thelancet.com
A 48-year-old man with poorly controlled HIV presented with severe human monkeypox virus
(hMPXV) infection, having completed 2 weeks of tecovirimat at another hospital. He had …

[PDF][PDF] Point of care nucleic acid testing for SARS-CoV-2 in hospitalized patients: a clinical validation trial and implementation study

…, PJ Lehner, MJ Siedner, H Zhang, CS Waddington… - Cell Reports …, 2020 - cell.com
There is an urgent need for rapid SARS-CoV-2 testing in hospitals to limit nosocomial spread.
We report an evaluation of point of care (POC) nucleic acid amplification testing (NAAT) in …

[HTML][HTML] Using a human challenge model of infection to measure vaccine efficacy: a randomised, controlled trial comparing the typhoid vaccines M01ZH09 with …

…, C Jones, CJ Blohmke, CS Waddington… - PLoS neglected …, 2016 - journals.plos.org
Background Typhoid persists as a major cause of global morbidity. While several licensed
vaccines to prevent typhoid are available, they are of only moderate efficacy and unsuitable …

[HTML][HTML] Exploiting genomics to mitigate the public health impact of antimicrobial resistance

C Waddington, ME Carey, CJ Boinett, E Higginson… - Genome Medicine, 2022 - Springer
Antimicrobial resistance (AMR) is a major global public health threat, which has been largely
driven by the excessive use of antimicrobials. Control measures are urgently needed to …

Evaluation of the Clinical and Microbiological Response to Salmonella Paratyphi A Infection in the First Paratyphoid Human Challenge Model

…, M Voysey, TC Darton, CS Waddington… - Clinical Infectious …, 2017 - academic.oup.com
Background. To expedite the evaluation of vaccines against paratyphoid fever, we aimed to
develop the first human challenge model of Salmonella enterica serovar Paratyphi A …