… , Jerry Nolan , George Rylance , Aziz Sheikh , David Joseph Unsworth … David Warrell …
Dr David Joseph Unsworth, Consultant Immunologist, North Bristol NHS Trust, Southmead …

We previously noted a region of amino acid sequence homology between A-gliadin, a
major alpha-gliadin component known to activate coeliac disease, and the early region E1b …

There are approximately 30 serum complement proteins (15% of the globulin fraction), excluding
cell surface receptors, and regulatory proteins. Many are manufactured in the liver, and …

Evidence for autoimmunity in diarrhoeal disease is reviewed. Firstly, coeliac disease (CD) is
considered. The incidence of tissue‐reactive autoantibodies in both adults and children with …

Alcohol and substance (drugs and/or alcohol) abuse are major risk factors for traumatic brain
injury (TBI); however, it remains unclear whether outcomes differ for those with and without …

A multi‐centre study is described in which thirty‐five adult patients with papillary IgA dermatitis
herpetiformis (DH) were compared with forty‐two patients with linear IgA deposits, of …

This review describes the mechanisms of the immune response to meningococcal disease,
examining the extent to which individual variation of the immune response can determine …

We report six patients with coeliac disease in whom arthritis was prominent at diagnosis and
who improved with dietary therapy. Joint pain preceded diagnosis by up to three years in …

Background: Published data imply that adult concentrations are achieved for all Ig isotypes
and plateau by 15--18 years of age. Recent data, however, suggest that these results are not …

Because coeliac disease often presents atypically it is underdiagnosed. It is suggested that
the detection rate may be increased by 12% if serology is used to identify cases of occult …