Grid search in hyperparameter optimization of machine learning models for prediction of HIV/AIDS test results

DM Belete, MD Huchaiah - International Journal of Computers and …, 2022 - Taylor & Francis
In this work, we propose hyperparameters optimization using grid search to optimize the
parameters of eight existing models and apply the best parameters to predict the outcomes of …

Assessment of risk factors and early presentations of Parkinson disease in primary care in a diverse UK population

…, S Marrium, J Robson, BM Jacobs, D Belete… - JAMA …, 2022 - jamanetwork.com
Importance Early features of Parkinson disease (PD) have been described through
population-based studies that overrepresent White, affluent groups and may not be generalizable. …

Parkinson's disease determinants, prediction and gene–environment interactions in the UK Biobank

BM Jacobs, D Belete, J Bestwick… - Journal of Neurology …, 2020 - jnnp.bmj.com
Objective To systematically investigate the association of environmental risk factors and
prodromal features with incident Parkinson’s disease (PD) diagnosis and the interaction of …

Gene-environment interactions in multiple sclerosis: a UK Biobank study

BM Jacobs, AJ Noyce, J Bestwick, D Belete… - Neurology …, 2021 - AAN Enterprises
Objective We sought to determine whether genetic risk modifies the effect of environmental
risk factors for multiple sclerosis (MS). To test this hypothesis, we tested for statistical …

Association between antiepileptic drugs and incident Parkinson disease

D Belete, BM Jacobs, C Simonet, JP Bestwick… - JAMA …, 2023 - jamanetwork.com
Importance Recent studies have highlighted an association between epilepsy and Parkinson
disease (PD). The role of antiepileptic drugs (AEDs) has not been explored. Objective To …

[HTML][HTML] Isolated headache is not a reliable indicator for brain cancer: the 2-week wait pathway for suspected CNS malignancies

B Ceronie, T Hart, D Belete, L Ramani, A Bahra - Clinical Medicine, 2021 - ncbi.nlm.nih.gov
Methods We retrospectively analysed all 2WW referrals for brain cancer between 2009 and
2016 in a district general neurology department. We compared clinical presentations to …

A comparative study of filter and wrapper methods on edhs–hiv/aids dataset

DM Belete, DH Manjaiah - 2020 Third International Conference …, 2020 - ieeexplore.ieee.org
Machine learning is currently recognized as an extremely valuable aspect for feature
selection. It is a subject often addressed in machine learning tasks particularly when there are …

[PDF][PDF] Wrapper based feature selection techniques on EDHS-HIV/AIDS dataset

DM Belete, DH Manjaiah - European Journal of Molecular & …, 2020 - researchgate.net
Selection of features is the mechanism that recognizes the most appropriate attributes and
elimination of the redundant and insignificant attributes. These research focuses on a feature …

Gene-environment interactions in Multiple Sclerosis: a UK Biobank study

BM Jacobs, A Noyce, J Bestwick, D Belete… - bioRxiv, 2020 - biorxiv.org
Importance Multiple Sclerosis (MS) is a common neuro-inflammatory disorder caused by a
combination of environmental exposures and genetic risk factors. Interaction between …

Classification of binary class hiv/aids test results using ensemble learning models

DM Belete, DH Manjaiah - 2020 International Conference on …, 2020 - ieeexplore.ieee.org
In HIV/AIDS datasets, there is lack of adequate and imbalanced samples includes repetitive
and unnecessary features that cause high dimensionality spaces. To address this problem, …