Background: A growing body of preclinical research suggests that brain glutamate systems
may be involved in the pathophysiology of major depression and the mechanism of action of …

Background: Antagonism of corticotropin‐releasing factor (CRF) receptors has been hypothesized
as a potential target for the development of novel anxiolytics. This study was designed …

Background The cognitive, behavioral, and mood effects ofN-methyl-D-aspartate (NMDA)
receptor antagonists, such as phencyclidine and ketamine, have been used to study the effects …

To investigate the efficacy and safety of intramuscular (IM) aripiprazole for the treatment of
agitation in patients with bipolar I disorder, manic or mixed episodes. In total, 301 patients …

Compared to traditional manufacturing methods, additive manufacturing and 3D printing
stand out in their ability to rapidly fabricate complex structures and precise geometries. The …

Freezing tolerance in plants develops through acclimation to cold by growth at low, above-freezing
temperatures. Wheat is one of the most freezing-tolerant plants among major crop …

OBJECTIVE: About 5% of pregnant women meet criteria for major depression. No
pharmacotherapy is specifically approved for antepartum depression; novel treatment approaches …

Introduction This double-blind, placebo-controlled study investigated the efficacy and safety
of intramuscular (IM) aripiprazole and IM haloperidol for the treatment of acute agitation in …

Background We aimed to describe the characteristics and in-hospital outcomes of ST-segment
elevation myocardial infarction (STEMI) patients during the Covid-19 era. Methods We …

Background: Bright light therapy was shown to be a promising treatment for depression
during pregnancy in a recent open-label study. In an extension of this work, we report findings …