User profiles for David EJ Jones

David Jones

Newcastle University
Verified email at ncl.ac.uk
Cited by 23508

[PDF][PDF] The UK‐PBC risk scores: derivation and validation of a scoring system for long‐term prediction of end‐stage liver disease in primary biliary cholangitis

…, HJ Cordell, GJ Alexander, DEJ Jones… - …, 2016 - Wiley Online Library
The biochemical response to ursodeoxycholic acid (UDCA)—so‐called “treatment response”—strongly
predicts long‐term outcome in primary biliary cholangitis (PBC). Several long‐…

Changing nomenclature for PBC: from 'cirrhosis' to 'cholangitis'

…, RG Gish, P Invernizzi, DEJ Jones… - Official journal of the …, 2015 - journals.lww.com
E-mail discussions among experts in the field before the meeting, as well as intense discussions
during the EASL Monothematic Conference in Milan with continual e-mail exchanges …

Sex and age are determinants of the clinical phenotype of primary biliary cirrhosis and response to ursodeoxycholic acid

…, SJ Ducker, RN Sandford, GJ Alexander, DEJ Jones… - Gastroenterology, 2013 - Elsevier
BACKGROUND, & AIMS: Studies of primary biliary cirrhosis (PBC) phenotypes largely have
been performed using small and selected populations. Study size has precluded …

Primary sclerosing cholangitis

JK Dyson, U Beuers, DEJ Jones, AW Lohse, M Hudson - The Lancet, 2018 - thelancet.com
Primary sclerosing cholangitis is a rare, chronic cholestatic liver disease characterised by
intrahepatic or extrahepatic stricturing, or both, with bile duct fibrosis. Inflammation and fibrosis …

The British Society of Gastroenterology/UK-PBC primary biliary cholangitis treatment and management guidelines

…, D Tiniakos, M Walmsley, G Webster, DEJ Jones - Gut, 2018 - gut.bmj.com
Primary biliary cholangitis (formerly known as primary biliary cirrhosis, PBC) is an autoimmune
liver disease in which a cycle of immune mediated biliary epithelial cell injury, cholestasis …

[HTML][HTML] Epithelial–mesenchymal transition contributes to portal tract fibrogenesis during human chronic liver disease

…, M Pekalski, L Zhao, TA Booth, DEJ Jones… - Laboratory …, 2008 - Elsevier
The relationship between bile duct damage and portal fibrosis in chronic liver diseases remains
unclear. This study was designed to show whether human intrahepatic biliary epithelial …

Cytotoxic T lymphocyte antigen-4 (CTLA-4) gene polymorphisms and susceptibility to type 1 autoimmune hepatitis

K Agarwal, AJ Czaja, DE Jones, PT Donaldson - Hepatology, 2000 - journals.lww.com
Genetic susceptibility to type 1 autoimmune hepatitis is indicated by a preponderance of female
subjects and strong associations with human leukocyte antigens (HLA) DRB1* 0301 and …

Development, validation, and evaluation of the PBC-40, a disease specific health related quality of life measure for primary biliary cirrhosis

…, D Buck, N Bhala, JL Newton, OFW James, DEJ Jones - Gut, 2005 - gut.bmj.com
Background and aims: Study of health related quality of life (HRQOL) and the factors responsible
for its impairment in primary biliary cirrhosis (PBC) has, to date, been limited. There is …

Familial primary biliary cirrhosis reassessed: a geographically-based population study

DEJ Jones, FE Watt, JV Metcalf, MF Bassendine… - Journal of …, 1999 - Elsevier
Background/Aims: Development of primary biliary cirrhosis in the close relatives of patients
with the disease has been reported in several series, suggesting a genetic component to …

British Society of Gastroenterology and UK-PSC guidelines for the diagnosis and management of primary sclerosing cholangitis

…, G Alexander, J Collier, JK Dyson, DEJ Jones… - Gut, 2019 - gut.bmj.com
These guidelines on the management of primary sclerosing cholangitis (PSC) were
commissioned by the British Society of Gastroenterology liver section. The guideline writing …