User profiles for David Herdman
 | David HerdmanNIHR Clinical Doctoral Research Fellow, King's College London Verified email at kcl.ac.uk Cited by 120 |
[HTML][HTML] TRPM8 on mucosal sensory nerves regulates colitogenic responses by innate immune cells via CGRP
TRPM8 is the molecular sensor for cold; however, the physiological role of TRPM8+
neurons at mucosal surfaces is unclear. Here we evaluated the distribution and peptidergic …
neurons at mucosal surfaces is unclear. Here we evaluated the distribution and peptidergic …
[HTML][HTML] Ion channel TRPV1-dependent activation of PTP1B suppresses EGFR-associated intestinal tumorigenesis
…, AI Triano, J Lee, Y Niv, DS Herdman… - The Journal of …, 2014 - Am Soc Clin Investig
The intestinal epithelium has a high rate of turnover, and dysregulation of pathways that
regulate regeneration can lead to tumor development; however, the negative regulators of …
regulate regeneration can lead to tumor development; however, the negative regulators of …
Vestibular deficits and psychological factors correlating to dizziness handicap and symptom severity
Objective To determine the relative contribution of demographic variables, objective testing
and psychological factors in explaining the variance in dizziness severity and handicap. …
and psychological factors in explaining the variance in dizziness severity and handicap. …
[HTML][HTML] The INVEST trial: a randomised feasibility trial of psychologically informed vestibular rehabilitation versus current gold standard physiotherapy for people with …
Background Persistent postural perceptual dizziness (PPPD) is a common and disabling
functional neuro-vestibular disorder. We aimed to determine the feasibility and acceptability of …
functional neuro-vestibular disorder. We aimed to determine the feasibility and acceptability of …
Inhibition of IRF4 in dendritic cells by PRR-independent and-dependent signals inhibit Th2 and promote Th17 responses
…, CM Kook, JM González-Navajas, DS Herdman… - Elife, 2020 - elifesciences.org
Cyclic AMP (cAMP) is involved in many biological processes but little is known regarding its
role in shaping immunity. Here we show that cAMP-PKA-CREB signaling (a pattern …
role in shaping immunity. Here we show that cAMP-PKA-CREB signaling (a pattern …
The Cognitive and Behavioural Responses to Symptoms Questionnaire (CBRQ): Development, reliability and validity across several long‐term conditions
Objectives Cognitive and behavioural responses to symptoms can worsen or maintain the
severity of symptoms across long‐term conditions (LTCs). Although the Cognitive and …
severity of symptoms across long‐term conditions (LTCs). Although the Cognitive and …
[HTML][HTML] The role of prediagnosis audiovestibular dysfunction versus distress, illness-related cognitions, and behaviors in predicted ongoing dizziness handicap
Objective People with chronic vestibular diseases experience variable degrees of self-perceived
disability. However, longitudinal data examining the predictive validity of relevant …
disability. However, longitudinal data examining the predictive validity of relevant …
[HTML][HTML] Integrating mental and physical health assessment in a neuro-otology clinic: feasibility, acceptability, associations and prevalence of common mental health …
D Herdman, H Sharma, A Simpson, L Murdin - Clinical Medicine, 2020 - ncbi.nlm.nih.gov
People with persistent physical symptoms are at risk of psychological symptoms, although
recognition in medical settings is low. This is a retrospective observational study of 954 …
recognition in medical settings is low. This is a retrospective observational study of 954 …
Validity of the patient health questionnaire anxiety and depression scale (PHQ-ADS) in patients with dizziness
Background: Co-occurrence of depressive, anxiety, and somatic symptoms are common.
The Patient Health Questionnaire-9 (PHQ-9) and Generalized Anxiety Disorder Scale-7 (GAD-7…
The Patient Health Questionnaire-9 (PHQ-9) and Generalized Anxiety Disorder Scale-7 (GAD-7…
Is 'persistent postural perceptual dizziness'a helpful diagnostic label? A qualitative exploratory study
D Herdman, A Evetovits, HD Everton… - Journal of Vestibular …, 2021 - content.iospress.com
BACKGROUND: Persistent Postural Perceptual Dizziness (PPPD) is a recently defined
functional syndrome. In other functional disorders there has been concern that the label itself can …
functional syndrome. In other functional disorders there has been concern that the label itself can …