User profiles for David Knight

David B Knight

Retired Professor, University of Guelph
Verified email at uoguelph.ca
Cited by 1757

Solvent-Free Oxidation of Primary Alcohols to Aldehydes Using Au-Pd/TiO2 Catalysts

…, AA Herzing, M Watanabe, CJ Kiely, DW Knight… - Science, 2006 - science.org
The oxidation of alcohols to aldehydes with O 2 in place of stoichiometric oxygen donors is
a crucial process for the synthesis of fine chemicals. However, the catalysts that have been …

Liquid crystalline spinning of spider silk

F Vollrath, DP Knight - Nature, 2001 - nature.com
Spider silk has outstanding mechanical properties despite being spun at close to ambient
temperatures and pressures using water as the solvent. The spider achieves this feat of …

Construction and initial characterization of a mouse-human chimeric anti-TNF antibody

DM Knight, HAN Trinh, J Le, S Siegel, D Shealy… - Molecular …, 1993 - Elsevier
Tumor necrosis factor-α (TNF) has been implicated in the pathogenesis of a variety of
human diseases including septic shock, cachexia, graft-versus-host disease and several …

A review of the clinical effects of phytoestrogens

DC Knight, JA Eden - Obstetrics & Gynecology, 1996 - journals.lww.com
Conclusion: This review suggests that phytoestrogens are among the dietary factors affording
protection against cancer and heart disease in vegetarians. With this epidemiologic and …

Chimeric anti-TNF-α monoclonal antibody cA2 binds recombinant transmembrane TNF-α and activates immune effector functions

BJ Scallon, MA Moore, H Trinh, DM Knight, J Ghrayeb - Cytokine, 1995 - Elsevier
Results of clinical trials have indicated that cA2, a neutralizing mouse/human IgG1 chimeric
anti-human TNF-α monoclonal antibody, may have therapeutic benefit for rheumatoid …

Solvent-free oxidation of primary carbon-hydrogen bonds in toluene using Au-Pd alloy nanoparticles

…, JA Lopez-Sanchez, SH Taylor, DW Knight… - Science, 2011 - science.org
Selective oxidation of primary carbon-hydrogen bonds with oxygen is of crucial importance
for the sustainable exploitation of available feedstocks. To date, heterogeneous catalysts …

[HTML][HTML] Premature birth and later insulin resistance

…, WE Jackson, C Jefferies, DB Knight… - … England Journal of …, 2004 - Mass Medical Soc
Background Term infants who are small for gestational age appear prone to the development
of insulin resistance during childhood. We hypothesized that insulin resistance, a marker of …

Second-generation SSRIs: human monoamine transporter binding profile of escitalopram and R-fluoxetine

MJ Owens, DL Knight, CB Nemeroff - Biological psychiatry, 2001 - Elsevier
Background: Single isomers of the selective serotonin reuptake inhibitors citalopram (escitalopram,
S-citalopram) and fluoxetine (R-fluoxetine) are currently under development for the …

[HTML][HTML] Mild hypercapnia or normocapnia after out-of-hospital cardiac arrest

…, A Ghosh, F Annoni, Y Chen, D Knight… - … England Journal of …, 2023 - Mass Medical Soc
Background Guidelines recommend normocapnia for adults with coma who are resuscitated
after out-of-hospital cardiac arrest. However, mild hypercapnia increases cerebral blood …

Identity and territory: geographical perspectives on nationalism and regionalism

DB Knight - Annals of the Association of American Geographers, 1982 - Taylor & Francis
Group politico-territorial identities are potent realities in our fragile world, yet geographers
have all but ignored them. Elements and processes involved in recognizing such territorially …