Background Proper assessment of the harms caused by the misuse of drugs can inform
policy makers in health, policing, and social care. We aimed to apply multicriteria decision …

Drug misuse and abuse are major health problems. Harmful drugs are regulated according
to classification systems that purport to relate to the harms and risks of each drug. However, …

Background Psilocybin is a serotonin receptor agonist that occurs naturally in some mushroom
species. Recent studies have assessed the therapeutic potential of psilocybin for various …

Psychedelic drugs have a long history of use in healing ceremonies, but despite renewed
interest in their therapeutic potential, we continue to know very little about how they work in the …

Background Psilocybin may have antidepressant properties, but direct comparisons between
psilocybin and established treatments for depression are lacking. Methods In a phase 2, …

For several decades, addiction has come to be viewed as a disorder of the dopamine
neurotransmitter system; however, this view has not led to new treatments. In this Opinion article, …

Entropy is a dimensionless quantity that is used for measuring uncertainty about the state of
a system but it can also imply physical qualities, where high entropy is synonymous with …

Amphetamine was discovered over 100 years ago. Since then, it has transformed from a drug
that was freely available without prescription as a panacea for a broad range of disorders …

Psilocybin therapy shows antidepressant potential, but its therapeutic actions are not well
understood. We assessed the subacute impact of psilocybin on brain function in two clinical …

These British Association for Psychopharmacology guidelines cover the range and aims of
treatment for anxiety disorders. They are based explicitly on the available evidence and are …