Patient non-compliance: deviance or reasoned decision-making?

JL Donovan, DR Blake - Social science & medicine, 1992 - Elsevier
A large quantity of research concerning issues of patient compliance with medications has
been produced in recent years. The assumption in much of this work is that patients have little …

A controlled pilot study of the utility of mirror visual feedback in the treatment of complex regional pain syndrome (type 1)

…, EFJ Ring, PW Halligan, PD Wall, DR Blake - …, 2003 - academic.oup.com
Background. We assessed mirror visual feedback (MVF) to test the hypothesis that incongruence
between motor output and sensory input produces complex regional pain syndrome (…

[HTML][HTML] Xanthine oxidoreductase catalyses the reduction of nitrates and nitrite to nitric oxide under hypoxic conditions

…, N Benjamin, R Eisenthal, R Harrison, DR Blake - FEBS letters, 1998 - Elsevier
Xanthine oxidoreductase (XOR) catalyses the reduction of the therapeutic organic nitrate,
nitroglycerin (glyceryl trinitrate, GTN), as well as inorganic nitrate and nitrite, to nitric oxide (NO…

Preliminary assessment of the efficacy, tolerability and safety of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis

DR Blake, P Robson, M Ho, RW Jubb… - Rheumatology, 2006 - academic.oup.com
Objectives. To assess the efficacy of a cannabis-based medicine (CBM) in the treatment of
pain due to rheumatoid arthritis (RA). Methods. We compared a CBM (Sativex) with placebo …

[HTML][HTML] Reduction of nitrite to nitric oxide catalyzed by xanthine oxidoreductase

…, DR Blake, CR Stevens, R Eisenthal, R Harrison - Journal of Biological …, 2000 - ASBMB
Xanthine oxidase (XO) was shown to catalyze the reduction of nitrite to nitric oxide (NO), under
anaerobic conditions, in the presence of either NADH or xanthine as reducing substrate. …

Chemiluminescence assay of mucosal reactive oxygen metabolites in inflammatory bowel disease

…, TRJ Stevens, R Niall, M Van Someren, DR Blake… - Gastroenterology, 1992 - Elsevier
Previous studies suggesting increased reactive oxygen metabolite (ROM) production in
inflammatory bowel disease have been restricted to peripheral blood and isolated intestinal …

Oxidants, inflammation, and anti‐inflammatory drugs

B Halliwell, JR Hoult, DR Blake - The FASEB journal, 1988 - Wiley Online Library
Species such as superoxide radical (O 2 − ), hydrogen peroxide (H 2 O 2 ), hydroxyl radical
( · OH), and hypochlorous acid (HOC1) can be formed in vivo, eg, by activated phagocytic …

Body perception disturbance: a contribution to pain in complex regional pain syndrome (CRPS)

…, P Kersten, CS McCabe, KM McPherson, DR Blake - PAIN®, 2007 - Elsevier
In spite of pain in the CRPS limb, clinical observations show patients pay little attention to,
and fail to care for, their affected limb as if it were not part of their body. Literature describes …

Generation of nitric oxide by a nitrite reductase activity of xanthine oxidase: a potential pathway for nitric oxide formation in the absence of nitric oxide synthase activity

…, PG Winyard, N Benjamin, DR Blake… - Biochemical and …, 1998 - Elsevier
Nitric oxide (NO) synthesis is now well-known to result from the oxidation of L-arginine by a
family of NO synthases (NOS). However, under hypoxic conditions this mechanism of NO …

Oxidative DNA damage and cellular sensitivity to oxidative stress in human autoimmune diseases.

S Bashir, G Harris, MA Denman, DR Blake… - Annals of the …, 1993 - ard.bmj.com
OBJECTIVES--To estimate the extent of genomic DNA damage and killing of lymphocytes
by reactive oxygen intermediates in autoimmune diseases. METHODS--8-Oxo-7-…