User profiles for Davinder PS Dosanjh
Davinder DosanjhUniversity of Birmingham Cited by 18524 |
Safety and efficacy of inhaled nebulised interferon beta-1a (SNG001) for treatment of SARS-CoV-2 infection: a randomised, double-blind, placebo-controlled, phase 2 …
…, TMA Wilkinson, MG Crooks, DPS Dosanjh… - The Lancet …, 2021 - thelancet.com
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection carries
a substantial risk of severe and prolonged illness; treatment options are currently limited. …
a substantial risk of severe and prolonged illness; treatment options are currently limited. …
Dynamic relationship between IFN-γ and IL-2 profile of Mycobacterium tuberculosis-specific T cells and antigen load
Distinct IFN-γ and IL-2 profiles of Ag-specific CD4+ T cells have recently been associated
with different clinical disease states and Ag loads in viral infections. We assessed the kinetics …
with different clinical disease states and Ag loads in viral infections. We assessed the kinetics …
Improved diagnostic evaluation of suspected tuberculosis
DPS Dosanjh, TSC Hinks, JA Innes… - Annals of internal …, 2008 - acpjournals.org
Background: The role of new T-cell–based blood tests for tuberculosis in the diagnosis of
active tuberculosis is unclear. Objective: To compare the performance of 2 interferon-γ assays …
active tuberculosis is unclear. Objective: To compare the performance of 2 interferon-γ assays …
Prognostic value of a T-cell–based, interferon-γ biomarker in children with tuberculosis contact
Background: Enzyme-linked immunospot (ELISpot) assay is an increasingly widely used, T-cell–based,
interferon-γ–release assay for diagnosing tuberculosis infection, but whether …
interferon-γ–release assay for diagnosing tuberculosis infection, but whether …
[HTML][HTML] Statin therapy in patients with community-acquired pneumonia
Community-acquired pneumonia (CAP) is the leading cause of death from infection in
developed countries. There is evidence of an association between improved survival from …
developed countries. There is evidence of an association between improved survival from …
[HTML][HTML] Dipeptidyl peptidase-1 inhibition in patients hospitalised with COVID-19: a multicentre, double-blind, randomised, parallel-group, placebo-controlled trial
…, J Underwood, A Hicks, DPS Dosanjh… - The Lancet …, 2022 - thelancet.com
Background Neutrophil serine proteases are involved in the pathogenesis of COVID-19 and
increased serine protease activity has been reported in severe and fatal infection. We …
increased serine protease activity has been reported in severe and fatal infection. We …
[HTML][HTML] Nebulised interferon-Β1a (SNG001) in hospitalised COVID-19: SPRINTER phase III study
…, MG Crooks, DPS Dosanjh… - ERJ open …, 2023 - Eur Respiratory Soc
Background Despite the availability of vaccines and therapies, patients are being hospitalised
with coronavirus disease 2019 (COVID-19). Interferon (IFN)-β is a naturally occurring …
with coronavirus disease 2019 (COVID-19). Interferon (IFN)-β is a naturally occurring …
[HTML][HTML] Novel M tuberculosis Antigen-Specific T-Cells Are Early Markers of Infection and Disease Progression
Background Mycobacterium tuberculosis Region-of-Difference-1 gene products present
opportunities for specific diagnosis of M. tuberculosis infection, yet immune responses to only …
opportunities for specific diagnosis of M. tuberculosis infection, yet immune responses to only …
Frequencies of region of difference 1 antigen-specific but not purified protein derivative-specific gamma interferon-secreting T cells correlate with the presence of …
TSC Hinks, DPS Dosanjh, JA Innes, G Pasvol… - Infection and …, 2009 - Am Soc Microbiol
The majority of individuals infected with Mycobacterium tuberculosis achieve lifelong immune
containment of the bacillus. What constitutes this effective host immune response is poorly …
containment of the bacillus. What constitutes this effective host immune response is poorly …
Use of T cell-based diagnosis of tuberculosis infection to optimize interpretation of tuberculin skin testing for child tuberculosis contacts
Background . Treatment of recent tuberculosis infection in children aged <2 years is
essential, because of high risk of progression to disease, but diagnosis is hindered by the …
essential, because of high risk of progression to disease, but diagnosis is hindered by the …