Purpose: Poly (ADP-ribose) polymerase (PARP) inhibitors are undergoing clinical evaluation
for cancer therapy. Because PARP inhibition has been shown to enhance tumor cell …

Purpose: Temozolomide, a DNA methylating agent, is currently undergoing clinical evaluation
for cancer therapy. Because temozolomide has been shown to increase survival rates of …

Aberrant DNA hypermethylation is a frequent finding in tumor cells, which has suggested that
inhibition of DNA methylation may be an effective cancer treatment strategy. Because DNA …

Purpose: The mitogen-activated protein (MAP) kinase pathway is important for cell proliferation,
survival, and differentiation, and is frequently up-regulated in cancers. The MAP kinase …

Residential segregation is most commonly measured with the index of dissimilarity, an indicator
that eliminates or at least minimizes the effect of group size. An asymmetric measure of …

Purpose: Because of the potential for affecting multiple signaling pathways, inhibition of
Hsp90 may provide a strategy for enhancing tumor cell radiosensitivity. Therefore, we have …

Vorinostat (suberoylanilide hydroxamic acid), a histone deacetylase inhibitor, is currently
undergoing clinical evaluation as therapy for cancer. We investigated the effects of vorinostat …

A new method is described for the analysis of atrazine and four of its degradation products (desethylatrazine,
deisopropylatrazine, didealkylatrazine, and hydroxyatrazine) in water. This …

It is clear that both voluntary and involuntary forces normally contribute to the residential
segregation existing between groups. For the most part, the contribution of each dimension has …

Anthropogenic organic contaminants in sediments from the Trenton Channel of the Detroit
River, a highly industrialized waterway connecting Lake St. Clair with Lake Erie, were …