[HTML][HTML] Iron accumulates in Huntington's disease neurons: protection by deferoxamine
Huntington’s disease (HD) is a progressive neurodegenerative disorder caused by a
polyglutamine-encoding CAG expansion in the huntingtin gene. Iron accumulates in the brains of …
polyglutamine-encoding CAG expansion in the huntingtin gene. Iron accumulates in the brains of …
Identification of 70 calcium-sensing receptor mutations in hyper-and hypo-calcaemic patients: evidence for clustering of extracellular domain mutations at calcium …
…, C Burren, JM Connell, H Jung, E Marks… - Human molecular …, 2012 - academic.oup.com
The calcium-sensing receptor (CaSR) is a G-protein-coupled receptor that has an
extracellular bilobed venus flytrap domain (VFTD) predicted to contain five calcium (Ca 2+ )-binding …
extracellular bilobed venus flytrap domain (VFTD) predicted to contain five calcium (Ca 2+ )-binding …
Impact of high iron intake on cognition and neurodegeneration in humans and in animal models: a systematic review
Context Accumulation of brain iron is linked to aging and protein-misfolding neurodegenerative
diseases. High iron intake may influence important brain health outcomes in later life. …
diseases. High iron intake may influence important brain health outcomes in later life. …
Vitamin D assessment in primary care: changing patterns of testing
Background Over recent years there has been increased interest in the disease burden
associated with vitamin D deficiency. This, combined with recognition that the prevalence of …
associated with vitamin D deficiency. This, combined with recognition that the prevalence of …
Estradiol regulates AQP2 expression in the collecting duct: a novel inhibitory role for estrogen receptor α
…, KA Hyndman, ES Marks… - American Journal …, 2015 - journals.physiology.org
While there is evidence that sex hormones influence multiple systems involved in salt and
water homeostasis, the question of whether sex hormones regulate aquaporin-2 (AQP2) and …
water homeostasis, the question of whether sex hormones regulate aquaporin-2 (AQP2) and …
Altered selenium status in Huntington's disease: neuroprotection by selenite in the N171-82Q mouse model
Z Lu, E Marks, J Chen, J Moline, L Barrows… - Neurobiology of …, 2014 - Elsevier
Disruption of redox homeostasis is a prominent feature in the pathogenesis of Huntington's
disease (HD). Selenium an essential element nutrient that modulates redox pathways and …
disease (HD). Selenium an essential element nutrient that modulates redox pathways and …
[HTML][HTML] Renal iron accumulation occurs in lupus nephritis and iron chelation delays the onset of albuminuria
ES Marks, ML Bonnemaison, SK Brusnahan… - Scientific reports, 2017 - nature.com
Proteins involved in iron homeostasis have been identified as biomarkers for lupus nephritis,
a serious complication of systemic lupus erythematosus (SLE). We tested the hypothesis …
a serious complication of systemic lupus erythematosus (SLE). We tested the hypothesis …
Assessing bone formation in patients with chronic kidney disease using procollagen type I N-terminal propeptide (PINP): The choice of assay makes a difference
A Tridimas, A Milan, E Marks - Annals of Clinical …, 2021 - journals.sagepub.com
Background Measurement of procollagen type I N-terminal propeptide (PINP) concentration
in serum reflects the rate of type I collagen synthesis and can therefore be used as a bone …
in serum reflects the rate of type I collagen synthesis and can therefore be used as a bone …
Interleukin-1β as a driver of renal NGAL production
ML Bonnemaison, ES Marks, EI Boesen - Cytokine, 2017 - Elsevier
Neutrophil gelatinase-associated lipocalin (NGAL) is increasingly regarded as a biomarker
of acute kidney injury, or kidney injury in general, but the stimuli responsible for its production …
of acute kidney injury, or kidney injury in general, but the stimuli responsible for its production …
Maternofetal inflammation induced for 2 wk in late gestation reduced birth weight and impaired neonatal growth and skeletal muscle glucose metabolism in lambs
…, RL Gibbs, ES Marks-Nelson… - Journal of animal …, 2021 - academic.oup.com
Intrauterine stress impairs growth and metabolism in the fetus and offspring. We recently
found that sustained maternofetal inflammation resulted in intrauterine growth-restricted (MI-…
found that sustained maternofetal inflammation resulted in intrauterine growth-restricted (MI-…