Huntington’s disease (HD) is a progressive neurodegenerative disorder caused by a
polyglutamine-encoding CAG expansion in the huntingtin gene. Iron accumulates in the brains of …

The calcium-sensing receptor (CaSR) is a G-protein-coupled receptor that has an
extracellular bilobed venus flytrap domain (VFTD) predicted to contain five calcium (Ca 2+ )-binding …

Context Accumulation of brain iron is linked to aging and protein-misfolding neurodegenerative
diseases. High iron intake may influence important brain health outcomes in later life. …

Background Over recent years there has been increased interest in the disease burden
associated with vitamin D deficiency. This, combined with recognition that the prevalence of …

While there is evidence that sex hormones influence multiple systems involved in salt and
water homeostasis, the question of whether sex hormones regulate aquaporin-2 (AQP2) and …

Disruption of redox homeostasis is a prominent feature in the pathogenesis of Huntington's
disease (HD). Selenium an essential element nutrient that modulates redox pathways and …

Proteins involved in iron homeostasis have been identified as biomarkers for lupus nephritis,
a serious complication of systemic lupus erythematosus (SLE). We tested the hypothesis …

Background Measurement of procollagen type I N-terminal propeptide (PINP) concentration
in serum reflects the rate of type I collagen synthesis and can therefore be used as a bone …

Neutrophil gelatinase-associated lipocalin (NGAL) is increasingly regarded as a biomarker
of acute kidney injury, or kidney injury in general, but the stimuli responsible for its production …

Background: Intrauterine growth restriction (IUGR) is associated with reduced β2 adrenergic
sensitivity, which contributes to poor postnatal muscle growth. The objective of this study …