Background Osteoarthritis (OA) is a degenerative joint disease involving the cartilage and
many of its surrounding tissues. Disease progression is usually slow but can ultimately lead to …

Bone mineral density (BMD) is the most widely used predictor of fracture risk. We performed
the largest meta-analysis to date on lumbar spine and femoral neck BMD, including 17 …

Introduction Epidemiological studies have shown that weaker grip strength in later life is
associated with disability, morbidity, and mortality. Grip strength is a key component of the …

Osteoporosis constitutes a major public health problem through its association with age-related
fractures, most notably those of the proximal femur. Substantial geographic variation has …

Osteoporosis is a major health problem, especially in elderly populations, and is associated
with fragility fractures at the hip, spine, and wrist. Hip fracture contributes to both morbidity …

A population‐based British cohort study, including ∼6% of the population, was used to derive
age‐ and sex‐specific incidence rates of fractures during childhood. Fractures were more …

This systematic review summarizes the effect of combined exercise and nutrition intervention
on muscle mass and muscle function. A total of 37 RCTs were identified. Results indicate …

Introduction With a worldwide ageing population, the importance of the prevention and
management of osteoporotic fragility fractures is increasing over time. In this review, we discuss …

RESEARCH DESIGN AND METHODS--A cross-sectional survey within a cohort study design
was used. Information was obtained on self-reported diabetes status cross-checked with …

OBJECTIVE Proinsulin is a precursor of mature insulin and C-peptide. Higher circulating
proinsulin levels are associated with impaired β-cell function, raised glucose levels, insulin …