Preliminary clinical data indicate that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
infection is associated with neurological and neuropsychiatric illness. Responding …

Background Although several disease-modifying treatments are available for relapsing multiple
sclerosis, treatment effects have been more modest in progressive multiple sclerosis and …

Background MS is a complex disease. Perhaps uniquely in neurology its clinical course is
characterised by two quite different clinical phases: the relapsing–remitting phase and a …

Background Opicinumab is a human monoclonal antibody against LINGO-1, an inhibitor of
oligodendrocyte differentiation and axonal regeneration. Previous findings suggested that …

CONTEXT: Palliative care is being advocated for noncancer patients but needs evidence of
effectiveness and cost-effectiveness. OBJECTIVE: We evaluated the cost-effectiveness of a …

Multiple sclerosis results in both physical and psychological disability but some patients
have needs that are not adequately met by existing services. Our objective was to explore …

Background: Mindfulness-based interventions have been shown to effectively reduce anxiety,
depression and pain in patients with chronic physical illnesses. Objectives: We assessed …

Fractures resulting from osteoporosis are a major cause of morbidity and mortality in the
developed world. People with multiple sclerosis experience reduced mobility and are …

Aim This study sought to assess symptom severity and prevalence in people severely
affected by multiple sclerosis (MS). Methods We collected data on symptoms and problems of …

Objective: The aims were (a) to test the effectiveness of a nurse-led cognitive behavioral
therapy (CBT) program to assist adjustment in the early stages of multiple sclerosis (MS) and (b) …