Review of current and future therapeutics in ABPA

E Lewington-Gower, L Chan… - Therapeutic advances in …, 2021 - journals.sagepub.com
Allergic bronchopulmonary aspergillosis is an allergic pulmonary condition caused by
hypersensitivity to antigens of Aspergillus sp. found most commonly in patients with underlying …

Simulation training as a tool to improve confidence in managing medical emergencies and leading cardiac arrests for core medical trainees

E Lewington-Gower, A Masding, M Carby… - Clinical …, 2019 - ncbi.nlm.nih.gov
Aims A simulation-based training course was designed with the aim of improving confidence
of core medical trainees (CMTs) in managing emergency presentations and cardiac arrest. …

[PDF][PDF] A Rare Occurrence of Adrenal Leiomyosarcoma

A Sharma, E Lewington-Gower… - Endocrine …, 2017 - postersessiononline.eu
• It was of heterogeneous density with delayed washout of contrast with a low-enhancing
centre.• The increase in size of the tumour within 6 months and the characteristics seen on …

Beyond the guidelines: treatment of allergic bronchopulmonary aspergillosis in cystic fibrosis

MG Tompkins, R Pettit - Annals of Pharmacotherapy, 2022 - journals.sagepub.com
Objective: To review the available literature addressing alternative allergic bronchopulmonary
aspergillosis (ABPA) treatment options for patients with cystic fibrosis (CF). Data Sources: …

Eosinophilic airway inflammation: role in asthma and chronic obstructive pulmonary disease

L George, CE Brightling - Therapeutic advances in chronic …, 2016 - journals.sagepub.com
The chronic lung diseases, asthma and chronic obstructive pulmonary disease (COPD), are
common affecting over 500 million people worldwide and causing substantial morbidity and …

Long-acting muscarinic receptor antagonists for the treatment of chronic airway diseases

K Alagha, A Palot, T Sofalvi, L Pahus… - … advances in chronic …, 2014 - journals.sagepub.com
Acetylcholine (neuronal and non-neuronal origin) regulates bronchoconstriction, and mucus
secretion. It has an inflammatory effect by inducing attraction, survival and cytokine release …

The management of refractory coeliac disease

J Woodward - Therapeutic Advances in Chronic Disease, 2013 - journals.sagepub.com
A significant proportion of patients with coeliac disease are ‘nonresponsive’ to gluten
withdrawal. Most cases of nonresponsive coeliac disease are due to persisting gluten ingestion. …

Targeting patients with asthma for omalizumab therapy: choosing the right patient to get the best value for money

A Al Said, B Cushen… - Therapeutic Advances in …, 2017 - journals.sagepub.com
The asthma syndrome has many manifestations, termed phenotypes, that arise by specific
cellular and molecular mechanisms, termed endotypes. Understanding an individual’s …

HP Acthar Gel (repository corticotropin injection) treatment of patients with multiple sclerosis and diabetes

C Kutz - Therapeutic Advances in Chronic Disease, 2016 - journals.sagepub.com
Background: Treatment of multiple sclerosis (MS) relapses can be complex in patients with
concomitant diabetes. Corticosteroids and adrenocorticotropic hormones are known to cause …

Current and future treatment options for cystic fibrosis lung disease: latest evidence and clinical implications

C Edmondson, JC Davies - Therapeutic advances in chronic …, 2016 - journals.sagepub.com
Treatment for cystic fibrosis (CF) has conventionally targeted downstream consequences of
the defect such as mucus plugging and infection. More recently, significant advances have …