The Hardy-Weinberg law plays an important role in the field of population genetics and often
serves as a basis for genetic inference. Because of its importance, much attention has been …

Maximum likelihood estimates (MLEs) in autologistic models and other exponential family
models for dependent data can be calculated with Markov chain Monte Carlo methods (the …

Markov chain Monte Carlo (MCMC; the Metropolis-Hastings algorithm) has been used for
many statistical problems, including Bayesian inference, likelihood inference, and tests of …

Background In this phase 2, randomized, double-blind, placebo-controlled, dose-ranging
study, we assessed the efficacy and safety of brodalumab (AMG 827), a human anti–interleukin…

Thompson shows how post-WWI Syrians and Lebanese mobilized to claim the terms of
citizenship enjoyed in the European metropole. Colonial Citizens highlights gender as a central …

The exosome complex of 3′–5′ exonucleases participates in RNA maturation and quality
control and can rapidly degrade RNA-protein complexes in vivo. However, the purified …

How can people appear moral to themselves when they fail to act morally? Two self-deception
strategies were considered:(a) misperceive one's behavior as moral and (b) avoid …

Pancreatic cancer is the most lethal common solid malignancy. Systemic therapies are often
ineffective, and predictive biomarkers to guide treatment are urgently needed. We …

… Thompson, Ryan Hastie, Angeliki Tsangaratou, Klaus Rajewsky, Sergei B. Koralov, and
Anjana Rao … Elizabeth C. Thompson …

The abnormally high number of centrosomes found in many human tumor cells can lead
directly to aneuploidy and genomic instability through the formation of multipolar mitotic spindles…