The benefit of evolving multidisciplinary care in ALS: a diagnostic cohort survival comparison
S Martin, E Trevor-Jones, S Khan, K Shaw… - … Lateral Sclerosis and …, 2017 - Taylor & Francis
Background: Care for people with amyotrophic lateral sclerosis (ALS) has altered at King’s
College Hospital over the last 20 years. The clinic has been a multidisciplinary, specialist, …
College Hospital over the last 20 years. The clinic has been a multidisciplinary, specialist, …
[HTML][HTML] Lessons of the month: Pyroglutamic acidosis: long-term paracetamol and a high anion gap
E Trevor-Jones, LT Hughes, R Robson… - Clinical …, 2020 - ncbi.nlm.nih.gov
An 84-year-old woman presented in extremis with confusion and Kussmaul respiration. She
had a history of urosepsis, renal impairment and osteoarthrosis. The venous blood gas …
had a history of urosepsis, renal impairment and osteoarthrosis. The venous blood gas …
A Further Possible Complication of Therapeutic Acetaminophen: Pyroglutamic Acidosis
E Trevor‐Jones, GW Stewart - Hepatology, 2021 - journals.lww.com
We read with interest the article by Louvet and colleagues in Hepatology, which describes
liver damage in the context of therapeutic doses of acetaminophen.(1) Simply to complete the …
liver damage in the context of therapeutic doses of acetaminophen.(1) Simply to complete the …
Early, specialist vocational rehabilitation to facilitate return to work after traumatic brain injury: the FRESH feasibility RCT.
K Radford, C Sutton, T Sach, J Holmes… - Health Technol …, 2018 - qmro.qmul.ac.uk
BACKGROUND: Up to 160,000 people incur traumatic brain injury (TBI) each year in the UK.
TBI can have profound effects on many areas of human functioning, including participation …
TBI can have profound effects on many areas of human functioning, including participation …
[HTML][HTML] Co-infections, secondary infections, and antimicrobial use in patients hospitalised with COVID-19 during the first pandemic wave from the ISARIC WHO CCP …
Background Microbiological characterisation of co-infections and secondary infections in
patients with COVID-19 is lacking, and antimicrobial use is high. We aimed to describe …
patients with COVID-19 is lacking, and antimicrobial use is high. We aimed to describe …
[HTML][HTML] Development and validation of the ISARIC 4C Deterioration model for adults hospitalised with COVID-19: a prospective cohort study
RK Gupta, EM Harrison, A Ho, AB Docherty… - The Lancet …, 2021 - thelancet.com
Background Prognostic models to predict the risk of clinical deterioration in acute COVID-19
cases are urgently required to inform clinical management decisions. Methods We …
cases are urgently required to inform clinical management decisions. Methods We …
[HTML][HTML] Characterisation of in-hospital complications associated with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol UK: a prospective …
Background COVID-19 is a multisystem disease and patients who survive might have in-hospital
complications. These complications are likely to have important short-term and long-…
complications. These complications are likely to have important short-term and long-…
[HTML][HTML] Risk of adverse outcomes in patients with underlying respiratory conditions admitted to hospital with COVID-19: a national, multicentre prospective cohort …
Background Studies of patients admitted to hospital with COVID-19 have found varying
mortality outcomes associated with underlying respiratory conditions and inhaled corticosteroid …
mortality outcomes associated with underlying respiratory conditions and inhaled corticosteroid …
[HTML][HTML] Non-steroidal anti-inflammatory drug use and outcomes of COVID-19 in the ISARIC Clinical Characterisation Protocol UK cohort: a matched, prospective …
Background Early in the pandemic it was suggested that pre-existing use of non-steroidal
anti-inflammatory drugs (NSAIDs) could lead to increased disease severity in patients with …
anti-inflammatory drugs (NSAIDs) could lead to increased disease severity in patients with …
[HTML][HTML] Changes in in-hospital mortality in the first wave of COVID-19: a multicentre prospective observational cohort study using the WHO Clinical Characterisation …
AB Docherty, RH Mulholland, NI Lone… - The Lancet …, 2021 - thelancet.com
Background Mortality rates in hospitalised patients with COVID-19 in the UK appeared to
decline during the first wave of the pandemic. We aimed to quantify potential drivers of this …
decline during the first wave of the pandemic. We aimed to quantify potential drivers of this …