The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
…, MS Wiesener, GW Chang, SC Clifford, EC Vaux… - Nature, 1999 - nature.com
Hypoxia-inducible factor-1 (HIF-1) has a key role in cellular responses to hypoxia, including
the regulation of genes involved in energy metabolism, angiogenesis and apoptosis 1 , 2 , 3 …
the regulation of genes involved in energy metabolism, angiogenesis and apoptosis 1 , 2 , 3 …
[HTML][HTML] Sustainability in quality improvement: redefining value
…, J Isherwood, A Wilkinson, E Vaux - Future healthcare …, 2018 - ncbi.nlm.nih.gov
Sustainability can be considered a domain of quality in healthcare, extending the
responsibility of health services to patients not just of today but of the future. The longer term …
responsibility of health services to patients not just of today but of the future. The longer term …
Regulation of hypoxia-inducible factor is preserved in the absence of a functioning mitochondrial respiratory chain
EC Vaux, E Metzen, KM Yeates… - Blood, The Journal of …, 2001 - ashpublications.org
Hypoxia-inducible factor (HIF) mediates a large number of transcriptional responses to
hypoxia and has an important role in processes that include angiogenesis and erythropoiesis. …
hypoxia and has an important role in processes that include angiogenesis and erythropoiesis. …
[HTML][HTML] How to get started in quality improvement
B Jones, E Vaux, A Olsson-Brown - Bmj, 2019 - bmj.com
Quality improvement (box 1) is a core component of many undergraduate and postgraduate
curriculums. 1 2 3 4 5 Numerous healthcare organisations, 6 professional regulators, 7 and …
curriculums. 1 2 3 4 5 Numerous healthcare organisations, 6 professional regulators, 7 and …
Use of real-time ultrasound guidance for the placement of hemodialysis catheters: a systematic review and meta-analysis of randomized controlled trials
KS Rabindranath, E Kumar, R Shail, E Vaux - American journal of kidney …, 2011 - Elsevier
BACKGROUND: Insertion of percutaneous hemodialysis catheters is an invasive procedure
with a small but definite risk of morbidity and mortality. OBJECTIVES: Assessing potential …
with a small but definite risk of morbidity and mortality. OBJECTIVES: Assessing potential …
Effect of buttonhole cannulation with a polycarbonate PEG on in-center hemodialysis fistula outcomes: a randomized controlled trial
E Vaux, J King, S Lloyd, J Moore, L Bailey… - American journal of …, 2013 - Elsevier
BACKGROUND: Quality improvement strategies to increase and maintain the numbers of
arteriovenous fistulas (AVFs) are a critical drive in enhancing the quality of care of patients …
arteriovenous fistulas (AVFs) are a critical drive in enhancing the quality of care of patients …
Ultrasound use for the placement of haemodialysis catheters
…, E Kumar, R Shail, EC Vaux - Cochrane Database of …, 2011 - cochranelibrary.com
Background A significant proportion of patients starting dialysis do so with a temporary or
tunnelled haemodialysis catheter. Insertion of these catheters can be achieved either by using …
tunnelled haemodialysis catheter. Insertion of these catheters can be achieved either by using …
Understanding the impact of haemodialysis on UK National Health Service patients' well‐being: A qualitative investigation
Aims and objectives While haemodialysis is an effective treatment for end‐stage renal disease,
the requirements and restrictions it imposes on patients can be onerous. The aim of this …
the requirements and restrictions it imposes on patients can be onerous. The aim of this …
Building the bridge to quality: an urgent call to integrate quality improvement and patient safety education with clinical care
…, F Moss, G Ogrinc, KG Shojania, E Vaux… - Academic …, 2020 - journals.lww.com
Current models of quality improvement and patient safety (QIPS) education are not fully
integrated with clinical care delivery, representing a major impediment toward achieving …
integrated with clinical care delivery, representing a major impediment toward achieving …
Choosing Wisely and the climate crisis: a role for clinicians
KB Born, W Levinson, E Vaux - BMJ Quality & Safety, 2024 - qualitysafety.bmj.com
There are growing calls for healthcare to confront it’s role in the climate crisis. Estimates suggest
that carbon emissions from healthcare constitute 5% of net global emissions. To put this …
that carbon emissions from healthcare constitute 5% of net global emissions. To put this …