Characterization of the inflammatory response to severe COVID-19 illness
…, K Hurley, S Walsh, E De Barra… - American journal of …, 2020 - atsjournals.org
… Eoghan de Barra … Eoghan de Barra … ), in which a loss of the integrity of the respiratory
epithelial barrier, coupled with de novo synthesis by airway neutrophils, led to passage of IL-6 into …
epithelial barrier, coupled with de novo synthesis by airway neutrophils, led to passage of IL-6 into …
[HTML][HTML] Readability of online COVID-19 health information: a comparison between four English speaking countries
…, KP Thornton, C McNally, SJ McConkey, E De Barra - BMC Public Health, 2020 - Springer
Background The internet is now the first line source of health information for many people
worldwide. In the current Coronavirus Disease 2019 (COVID-19) global pandemic, health …
worldwide. In the current Coronavirus Disease 2019 (COVID-19) global pandemic, health …
[HTML][HTML] A phase Ia study to assess the safety and immunogenicity of new malaria vaccine candidates ChAd63 CS administered alone and with MVA CS
Background Plasmodium falciparum (P. falciparum) malaria remains a significant cause of
mortality and morbidity throughout the world. Development of an effective vaccine would be a …
mortality and morbidity throughout the world. Development of an effective vaccine would be a …
Factors associated with successful completion of outpatient parenteral antibiotic therapy (OPAT): a 10-year review from a large West London service
…, G Satta, E Brannigan, E De Barra… - International journal of …, 2019 - Elsevier
Outpatient parenteral antibiotic therapy (OPAT) is an established antimicrobial delivery method
in the UK. OPAT services differ nationwide, with a paucity of high-quality outcome data to …
in the UK. OPAT services differ nationwide, with a paucity of high-quality outcome data to …
Identification of distinct long COVID clinical phenotypes through cluster analysis of self-reported symptoms
…, C O'Broin, ER Feeney, E De Barra… - Open forum …, 2022 - academic.oup.com
Background We aimed to describe the clinical presentation of individuals presenting with
prolonged recovery from coronavirus disease 2019 (COVID-19), known as long COVID. …
prolonged recovery from coronavirus disease 2019 (COVID-19), known as long COVID. …
Von Willebrand factor propeptide in severe coronavirus disease 2019 (COVID‐19): evidence of acute and sustained endothelial cell activation
…, AP Worrall, C Kelly, E de Barra… - British journal of …, 2021 - Wiley Online Library
Endothelial cell (EC) activation plays a key role in the pathogenesis of pulmonary
microvascular occlusion, which is a hallmark of severe coronavirus disease 2019 (COVID‐19). …
microvascular occlusion, which is a hallmark of severe coronavirus disease 2019 (COVID‐19). …
Evaluation of the efficacy of ChAd63-MVA vectored vaccines expressing circumsporozoite protein and ME-TRAP against controlled human malaria infection in malaria …
…, NA Anagnostou, E De Barra… - The Journal of …, 2015 - academic.oup.com
Background. Circumsporozoite protein (CS) is the antigenic target for RTS,S, the most
advanced malaria vaccine to date. Heterologous prime-boost with the viral vectors simian …
advanced malaria vaccine to date. Heterologous prime-boost with the viral vectors simian …
ADAMTS13 regulation of VWF multimer distribution in severe COVID‐19
…, AP Worrall, C Kelly, E de Barra… - … of Thrombosis and …, 2021 - Wiley Online Library
Background Consistent with fulminant endothelial cell activation, elevated plasma von
Willebrand factor (VWF) antigen levels have been reported in patients with COVID‐19. The …
Willebrand factor (VWF) antigen levels have been reported in patients with COVID‐19. The …
[HTML][HTML] An integrated multidisciplinary model of COVID-19 recovery care
…, D Gillan, N Pender, H Barry, E de Barra… - Irish Journal of Medical …, 2021 - Springer
Background In January 2020, the WHO declared the SARS-CoV-2 outbreak a public health
emergency; by March 11, a pandemic was declared. To date in Ireland, over 3300 patients …
emergency; by March 11, a pandemic was declared. To date in Ireland, over 3300 patients …
Safety and High Level Efficacy of the Combination Malaria Vaccine Regimen of RTS,S/AS01B With Chimpanzee Adenovirus 63 and Modified Vaccinia Ankara …
…, RO Payne, N Venkatraman, E De Barra… - The Journal of …, 2016 - academic.oup.com
Background. The need for a highly efficacious vaccine against Plasmodium falciparum remains
pressing. In this controlled human malaria infection (CHMI) study, we assessed the safety…
pressing. In this controlled human malaria infection (CHMI) study, we assessed the safety…