Hypermethylation of multiple genes in tumor tissues and voided urine in urinary bladder cancer patients
…, HY Cheung, WS Wong, PSF Chan, FMM Lai… - Clinical Cancer …, 2002 - AACR
Purpose: We aimed to investigate the methylation pattern in bladder cancer and assess the
diagnostic potential of such epigenetic changes in urine. Experimental Design: The …
diagnostic potential of such epigenetic changes in urine. Experimental Design: The …
[HTML][HTML] Intrarenal expression of microRNAs in patients with IgA nephropathy
G Wang, BCH Kwan, FMM Lai, PCL Choi… - Laboratory …, 2010 - Elsevier
MicroRNAs (miRNAs) are noncoding, single-stranded RNA molecules that have important
roles in a number of physiological and pathological processes. Previous studies have proved …
roles in a number of physiological and pathological processes. Previous studies have proved …
Prevalence and clinicopathological characteristics of islet amyloid in Chinese patients with type 2 diabetes
HL Zhao, FMM Lai, PCY Tong, DR Zhong, D Yang… - Diabetes, 2003 - Am Diabetes Assoc
Islet amyloid has been suggested to be an important link between insulin resistance and β-cell
dysfunction in type 2 diabetes. To investigate the prevalence and clinicopathological …
dysfunction in type 2 diabetes. To investigate the prevalence and clinicopathological …
Expression and functional study of estrogen receptor-related receptors in human prostatic cells and tissues
Estrogen receptor-related receptors (ERRs; α, β, γ) are orphan nuclear receptors and
constitutively active without binding to estrogen. Like estrogen receptors (ERs), ERRs bind to …
constitutively active without binding to estrogen. Like estrogen receptors (ERs), ERRs bind to …
Up-regulated pancreatic tissue microRNA-375 associates with human type 2 diabetes through β-cell deficit and islet amyloid deposition
…, Y Sui, L He, JJ Siu, PP Patty, PCY Tong, FMM Lai… - Pancreas, 2010 - journals.lww.com
Objectives: The aim of this study was to examine correlations of the islet-specific microRNA-375
expression to islet amyloid formation and pancreatic islet damage in human type 2 …
expression to islet amyloid formation and pancreatic islet damage in human type 2 …
Frequent hypermethylation of promoter region of RASSF1A in tumor tissues and voided urine of urinary bladder cancer patients
…, WS Wong, PSF Chan, FMM Lai… - … journal of cancer, 2003 - Wiley Online Library
High frequency loss of 3p21.3 region where RASSF1A located was demonstrated in several
tumors. We aimed to investigate the methylation status of RASSF1A and the frequency of …
tumors. We aimed to investigate the methylation status of RASSF1A and the frequency of …
[HTML][HTML] Fat redistribution and adipocyte transformation in uninephrectomized rats
…, X Zhu, RR Fan, G Xu, APS Kong, CS Ho, FMM Lai… - Kidney international, 2008 - Elsevier
Dyslipidemia complicates renal function leading to disturbances of major homeostatic
organs in the body. Here we examined the effect of chronic renal dysfunction induced by …
organs in the body. Here we examined the effect of chronic renal dysfunction induced by …
Follicular dendritic cell sarcoma of the neck: report of two cases complicated by pulmonary metastases
PCL Choi, KF To, FMM Lai, TW Lee, APC Yim… - Cancer, 2000 - Wiley Online Library
BACKGROUND Follicular dendritic cell (FDC) sarcoma is an uncommon neoplasm occurring
primarily in lymph nodes but also in extranodal sites. A correct diagnosis can be difficult to …
primarily in lymph nodes but also in extranodal sites. A correct diagnosis can be difficult to …
Amyloid oligomers in diabetic and nondiabetic human pancreas
…, J Guan, L He, XM Gu, HK Wong, L Baum, FMM Lai… - Translational …, 2009 - Elsevier
The amyloid hypothesis of type 2 diabetes mellitus postulates that elevated levels of
normally expressed monomeric proteins of human islet amyloid polypeptide (hIAPP) trigger …
normally expressed monomeric proteins of human islet amyloid polypeptide (hIAPP) trigger …
Impact of experimental acute hyponatremia on severe traumatic brain injury in rats: influences on injuries, permeability of blood–brain barrier, ultrastructural features …
C Ke, WS Poon, HK Ng, FMM Lai, NLS Tang… - Experimental …, 2002 - Elsevier
… A 2-mm burr hole was made 5 mm posterior to the bregma and 3.5 mm right lateral to the …
) was defined as the sum of all contusion areas multiplied by 0.1 mm. To exclude possible …
) was defined as the sum of all contusion areas multiplied by 0.1 mm. To exclude possible …