Disease stratification in GCA and PMR: state of the art and future perspectives
…, MA Khurshid, A Sebastian, F Coath… - Nature Reviews …, 2023 - nature.com
Giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) are closely related conditions
characterized by systemic inflammation, a predominant IL-6 signature, an excellent response …
characterized by systemic inflammation, a predominant IL-6 signature, an excellent response …
[PDF][PDF] A probability score to aid the diagnosis of suspected giant cell arteritis
F Laskou, F Coath, SL Mackie, S Banerjee… - Clin Exp …, 2019 - clinexprheumatol.org
Objective. We propose a GCA probability score intended to help to riskstratify patients
referred by general practitioners with suspected GCA into those with high probability of GCA …
referred by general practitioners with suspected GCA into those with high probability of GCA …
Axial presentation of reactive arthritis secondary to COVID-19 infection
FL Coath, J Mackay, JK Gaffney - Rheumatology, 2021 - academic.oup.com
DEAR EDITOR, the novel coronavirus SARS-CoV-2, known as COVID-19, is continually
being observed to cause new and varied multisystem sequalae. There have been several …
being observed to cause new and varied multisystem sequalae. There have been several …
Role of the halo sign in the assessment of giant cell arteritis: a systematic review and meta-analysis
A Sebastian, F Coath, S Innes, J Jackson… - … advances in practice, 2021 - academic.oup.com
Objectives This systematic review and meta-analysis aimed to evaluate the diagnostic value
of the halo sign in the assessment of GCA. Methods A systematic literature review was …
of the halo sign in the assessment of GCA. Methods A systematic literature review was …
Ultrasonography in the diagnosis and follow-up of giant cell arteritis
FL Coath, C Mukhtyar - Rheumatology, 2021 - academic.oup.com
Colour Doppler ultrasonography is the first measure to allow objective bedside assessment
of GCA. This article discusses the evidence using the OMERACT filter. Consensus …
of GCA. This article discusses the evidence using the OMERACT filter. Consensus …
Quality standards for the care of people with giant cell arteritis in secondary care
FL Coath, M Bukhari, G Ducker, B Griffiths… - …, 2023 - academic.oup.com
Objective GCA is the commonest primary systemic vasculitis in adults, with significant health
economic costs and societal burden. There is wide variation in access to secondary care …
economic costs and societal burden. There is wide variation in access to secondary care …
Giant cell arteritis: new concepts, treatments and the unmet need that remains
F Coath, K Gillbert, B Griffiths, F Hall, L Kay… - …, 2019 - academic.oup.com
This is an exciting time for the management of GCA. The National Institute for Health and Care
Excellence (NICE) and NHS England have approved tocilizumab (TCZ), an IL-6 receptor …
Excellence (NICE) and NHS England have approved tocilizumab (TCZ), an IL-6 receptor …
[HTML][HTML] Halo score (temporal artery, its branches and axillary artery) as a diagnostic, prognostic and disease monitoring tool for Giant Cell Arteritis (GCA)
A Sebastian, KSM van der Geest, F Coath, P Gondo… - BMC rheumatology, 2020 - Springer
Background Giant cell arteritis (GCA) is a common large vessel vasculitis of the elderly, often
associated with sight loss. Glucocorticoids (GC remain the mainstay of treatment, although …
associated with sight loss. Glucocorticoids (GC remain the mainstay of treatment, although …
'Slope sign': a feature of large vessel vasculitis?
B Dasgupta, K Smith, AAS Khan, F Coath… - Annals of the …, 2019 - ard.bmj.com
Ultrasound (US) scanning in the diagnosis of large vessel giant cell arteritis (LV-GCA) is
becoming more prevalent, with the advantage of being non-invasive and free of ionising …
becoming more prevalent, with the advantage of being non-invasive and free of ionising …
Long-term efficacy and safety of Leflunomide in large-vessel giant cell arteritis: A single-center, 10-year experience
A Tomelleri, F Coath, A Sebastian… - JCR: Journal of …, 2022 - journals.lww.com
Study Design Only patients treated with leflunomide were included. First, demographic
characteristics, disease duration before leflunomide start, previous and concomitant therapies, …
characteristics, disease duration before leflunomide start, previous and concomitant therapies, …