Physiotherapy and occupational therapy vs no therapy in mild to moderate Parkinson disease: a randomized clinical trial

CE Clarke, S Patel, N Ives, CE Rick, F Dowling… - JAMA …, 2016 - jamanetwork.com
Importance It is unclear whether physiotherapy and occupational therapy are clinically
effective and cost-effective in Parkinson disease (PD). Objective To perform a large pragmatic …

Long-term effectiveness of adjuvant treatment with catechol-O-methyltransferase or monoamine oxidase B inhibitors compared with dopamine agonists among …

…, T Boodell, VC Cheed, J Daniels, F Dowling… - JAMA …, 2022 - jamanetwork.com
Importance Many people with Parkinson disease (PD) develop motor complications that are
uncontrolled by levodopa dose adjustment. Among these patients, it is uncertain which drug …

PRedicting Outcomes For Crohn's dIsease using a moLecular biomarkEr (PROFILE): protocol for a multicentre, randomised, biomarker-stratified trial

M Parkes, NM Noor, F Dowling, H Leung, S Bond… - BMJ open, 2018 - bmjopen.bmj.com
Background The course of Crohn’s disease (CD) varies substantially between individuals,
but reliable prognostic markers do not exist. This hinders disease management because …

Pediatric trampoline injuries

…, DP Moore, EE Fogarty, FE Dowling - Journal of Pediatric …, 2007 - journals.lww.com
Methods: We prospectively recorded details of patients presenting to our institution, Our
Lady's Children's Hospital, Crumlin (Dublin, Ireland), during the busy summer months of June, …

[HTML][HTML] Lee Silverman Voice Treatment versus standard speech and language therapy versus control in Parkinson's disease: a pilot randomised controlled trial (PD …

…, N Ives, S Patel, R Woolley, F Dowling… - Pilot and Feasibility …, 2018 - Springer
Background Speech-related problems are common in Parkinson’s disease (PD), but there is
little evidence for the effectiveness of standard speech and language therapy (SLT) or Lee …

Trial summary and protocol for a phase II randomised placebo-controlled double-blinded trial of Interleukin 1 blockade in Acute Severe Colitis: the IASO trial

MG Thomas, C Bayliss, S Bond, F Dowling, J Galea… - BMJ open, 2019 - bmjopen.bmj.com
Introduction Acute severe ulcerative colitis (ASUC) is a severe manifestation of ulcerative colitis
(UC) that warrants hospitalisation. Despite significant advances in therapeutic options for …

[HTML][HTML] Lee Silverman voice treatment versus standard NHS speech and language therapy versus control in Parkinson's disease (PD COMM pilot): study protocol for …

…, MC Brady, N Ives, R Patel, H Roberts, F Dowling… - Trials, 2014 - Springer
Background Parkinson’s disease is a common movement disorder affecting approximately
127,000 people in the UK, with an estimated two thirds having speech-related problems. …

[HTML][HTML] PROphylaxis for paTiEnts at risk of COVID-19 infecTion (PROTECT-V)

…, W Qian, V Jha, K Gatley, R Adhikari, F Dowling… - Trials, 2023 - Springer
Background Despite the introduction of vaccination, there remains a need for pre-exposure
prophylactic agents against SARS-CoV-2. Several patient groups are more vulnerable to …

Refining Ovarian Cancer Test accuracy Scores (ROCkeTS): protocol for a prospective longitudinal test accuracy study to validate new risk scores in women with …

S Sundar, C Rick, F Dowling, P Au, K Snell, N Rai… - Bmj Open, 2016 - bmjopen.bmj.com
Introduction Ovarian cancer (OC) is associated with non-specific symptoms such as bloating,
making accurate diagnosis challenging: only 1 in 3 women with OC presents through …

Rating the intelligibility of dysarthic speech amongst people with Parkinson's Disease: a comparison of trained and untrained listeners

…, A Rontiris, L Knox-Smith, F Dowling… - Clinical linguistics & …, 2019 - Taylor & Francis
Intelligibility of speech is a key outcome in speech and language therapy (SLT) and research.
SLT students frequently participate as raters of intelligibility but we lack information about …