User profiles for George Kinghorn

George Kinghorn

Honorary Professor in Genitourinary Medicine
Verified email at sheffield.ac.uk
Cited by 6642

Imiquimod and resiquimod as novel immunomodulators

DH Dockrell, GR Kinghorn - Journal of Antimicrobial …, 2001 - academic.oup.com
Augmenting the host's natural immune response to viruses by the administration of exogenous
cytokines such as interferon-α (IFN-α) is a strategy increasingly employed in antiviral …

A randomized controlled trial of a replication defective (gH deletion) herpes simplex virus vaccine for the treatment of recurrent genital herpes among …

…, J Lalezari, RC Brady, M Shahmanesh, G Kinghorn… - Vaccine, 2006 - Elsevier
BACKGROUND: A replication incompetent herpes virus lacking the glycoprotein H gene has
been developed as a potential therapeutic vaccine for genital herpes. GOAL: To determine …

How much do delayed healthcare seeking, delayed care provision, and diversion from primary care contribute to the transmission of STIs?

…, E Jungmann, J Sweeney, G Kinghorn… - Sexually Transmitted …, 2007 - sti.bmj.com
… offered an appointment within 48 h (George Kinghorn, personal communication). We are …
rebooking is less common among teenagers (George Kinghorn, personal communication). …

[HTML][HTML] Astodrimer sodium antiviral nasal spray for reducing respiratory infections is safe and well tolerated in a randomized controlled trial

…, GP Heery, A Seta, CA Luscombe, GR Kinghorn… - Scientific Reports, 2022 - nature.com
Astodrimer sodium is a dendrimer molecule with antiviral and virucidal activity against SARS-CoV-2
and other respiratory viruses in vitro, and has previously been shown to be safe and …

[HTML][HTML] A phase 2, double-blind, multicenter, randomized, placebo-controlled, dose‑ranging study of the efficacy and safety of Astodrimer Gel for the treatment of …

…, A Castellarnau, P McCloud, GR Kinghorn - PLoS …, 2020 - journals.plos.org
Background Astodrimer Gel contains a novel dendrimer intended to treat and prevent
bacterial vaginosis. We assessed the efficacy and safety of Astodrimer Gel for treatment of …

In-vitro and in-vivo activity of metronidazole against Gardnerella vaginalis, Bacteroides spp. and Mobiluncus spp. in bacterial vaginosis

…, AB Alawattegama, GR Kinghorn… - Journal of …, 1985 - academic.oup.com
An open, randomized, culture-controlled clinical study was designed to compare the efficacy
of a single 2 g dose of metronidazole (Elyzol) with standard 7-day therapy in the treatment …

[HTML][HTML] Rising population cost for treating people living with HIV in the UK, 1997-2013

…, G Baily, R Brettle, M Fisher, M Gompels, G Kinghorn… - PloS one, 2010 - journals.plos.org
Background The number of people living with HIV (PLHIV) is increasing in the UK. This study
estimated the annual population cost of providing HIV services in the UK, 1997–2006 and …

Concordance between Neisseria gonorrhoeae Genotypes Recovered from Known Sexual Contacts

N Bilek, IM Martin, G Bell, GR Kinghorn… - Journal of clinical …, 2007 - Am Soc Microbiol
Neisseria gonorrhoeae multiantigen sequence typing (NG-MAST) is a highly discriminatory
molecular typing procedure that provides precise and unambiguous strain characterization. …

Characteristics of those who repeatedly acquire sexually transmitted infections: a retrospective cohort study of attendees at three urban sexually transmitted disease …

…, KA Fenton, PA Rogers, GR Kinghorn… - Sexually transmitted …, 2001 - journals.lww.com
Characteristics of Those Who Repeatedly Acquire Sexually Tra... : Sexually Transmitted
Diseases Characteristics of Those Who Repeatedly Acquire Sexually Transmitted Infections: A …

Trends in sexually transmitted infections in general practice 1990-2000: population based study using data from the UK general practice research database

…, I Petersen, A Islam, MG Brook, JD Ross, GR Kinghorn… - Bmj, 2006 - bmj.com
Objective To describe the contribution of primary care to the diagnosis and management of
sexually transmitted infections in the United Kingdom, 1990-2000, in the context of increasing …