This document aims to provide practical guidance for the assessment and management of
patients with thrombocytopenia, with a particular focus on immune thrombocytopenia (ITP), …

The cornerstone of life-saving therapy in immune-mediated thrombotic thrombocytopenic
purpura (iTTP) has been plasma exchange (PEX) combined with immunomodulatory strategies…

Background The ISTH bleeding assessment tool ( ISTH ‐ BAT ) was developed to record
bleeding symptoms and to aid diagnosis in patients with a possible bleeding disorder. …

Inherited thrombocytopenias are a heterogeneous group of disorders characterized by
abnormally low platelet counts which can be associated with abnormal bleeding. Next-generation …

We analyzed candidate platelet function disorder genes in 13 index cases with a history of
excessive bleeding in association with a significant reduction in dense granule secretion and …

Light transmission aggregometry (LTA) is used worldwide for the investigation of heritable
platelet function disorders (PFDs), but interpretation of results is complicated by the feedback …

Background The strategies that parents use to guide and discipline their children may
influence their emotional health. Relatively little research has been conducted examining the …

Acute antibody-mediated thrombotic thrombocytopenic purpura (TTP) is a thrombotic
microangiopathy with high morbidity and mortality. Rituximab is highly effective as prophylaxis in …

Inherited thrombocytopenias are a group of disorders that are characterized by a low platelet
count and are sometimes associated with excessive bleeding that ranges from mild to …

… Gillian A. Lowe 3 … A medium effect size was chosen for the sample size calculations based
on past research using Caribbean samples ( Lipps et al., 2012 ; Lowe et al., 2009 ). Results of …