Glycoprotein structure determination by mass spectrometry
The human genome encodes 30,000 to 40,000 proteins, and a major challenge is to understand
how posttranslational events, such as glycosylation, affect the activities and functions of …
how posttranslational events, such as glycosylation, affect the activities and functions of …
Visual dysfunction in Parkinson's disease
Patients with Parkinson’s disease have a number of specific visual disturbances. These include
changes in colour vision and contrast sensitivity and difficulties with complex visual tasks …
changes in colour vision and contrast sensitivity and difficulties with complex visual tasks …
Progress towards therapies for disease modification in Parkinson's disease
…, T Simuni, O Bandmann, HR Morris… - The Lancet …, 2021 - thelancet.com
The development of interventions to slow or halt the progression of Parkinson's disease
remains a priority for patients and researchers alike. To date, no agents have been shown to …
remains a priority for patients and researchers alike. To date, no agents have been shown to …
Identification of two related pentapeptides from the brain with potent opiate agonist activity
…, HW Kosterlitz, LA Fothergill, BA Morgan, HR Morris - Nature, 1975 - nature.com
Enkephalin, a natural ligand for opiate receptors is composed of the pentapeptides H–Tyr–Gly–Gly–Phe–Met–OH
and H–Tyr–Gly–Gly–Phe–Leu–OH. The evidence is based on the …
and H–Tyr–Gly–Gly–Phe–Leu–OH. The evidence is based on the …
Clinical diagnosis of progressive supranuclear palsy: the movement disorder society criteria
Background: PSP is a neuropathologically defined disease entity. Clinical diagnostic criteria,
published in 1996 by the National Institute of Neurological Disorders and Stroke/Society for …
published in 1996 by the National Institute of Neurological Disorders and Stroke/Society for …
Calcitonin gene-related peptide is a potent vasodilator
A novel peptide, calcitonin gene-related peptide (CGRP), has been predicted to result from
alternative processing of the primary RNA transcript of the calcitonin gene in the rat 1,2 . …
alternative processing of the primary RNA transcript of the calcitonin gene in the rat 1,2 . …
[PDF][PDF] A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD
… by Santa Cruz, sc-138763, 1:30) and secondary antibody (Alexa488-conjugated anti-rabbit
antibody by Invitrogen, 1:200) were diluted in 5% FBS and incubated at 37 C for 3 hr or 30 …
antibody by Invitrogen, 1:200) were diluted in 5% FBS and incubated at 37 C for 3 hr or 30 …
Sequence and structure of a human glucose transporter
The amino acid sequence of the glucose transport protein from human HepG2 hepatoma
cells was deduced from analysis of a complementary DNA clone. Structural analysis of the …
cells was deduced from analysis of a complementary DNA clone. Structural analysis of the …
Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies
Background Genome-wide association studies (GWAS) in Parkinson's disease have increased
the scope of biological knowledge about the disease over the past decade. We aimed to …
the scope of biological knowledge about the disease over the past decade. We aimed to …
[HTML][HTML] Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study
Background We aimed to accurately estimate the frequency of a hexanucleotide repeat
expansion in C9orf72 that has been associated with a large proportion of cases of amyotrophic …
expansion in C9orf72 that has been associated with a large proportion of cases of amyotrophic …