[HTML][HTML] Genomic and epigenetic evidence for oxytocin receptor deficiency in autism

…, CA Markunas, C Lintas, RK Abramson, HH Wright… - BMC medicine, 2009 - Springer
Background Autism comprises a spectrum of behavioral and cognitive disturbances of
childhood development and is known to be highly heritable. Although numerous approaches …

Factor analysis of restricted and repetitive behaviors in autism using the Autism Diagnostic Interview-R

…, RK Abramson, SA Ravan, HH Wright… - Child psychiatry and …, 2003 - Springer
The current study examined the factor structure of restricted and repetitive behaviors (RRB)
in children with autism. Factor extraction procedures of 12 items from the Autism Diagnostic …

A genome‐wide association study of autism reveals a common novel risk locus at 5p14. 1

…, JL McCauley, GW Beecham, HH Wright… - Annals of human …, 2009 - Wiley Online Library
Although autism is one of the most heritable neuropsychiatric disorders, its underlying genetic
architecture has largely eluded description. To comprehensively examine the hypothesis …

Genomic screen and follow‐up analysis for autistic disorder

…, JM Vance, RH Abramson, HH Wright… - American journal of …, 2002 - Wiley Online Library
Autistic disorder (AutD) is a neurodevelopmental disorder characterized by significant
impairment in social, communicative, and behavioral functioning. A genetic basis for AutD is well …

Accelerated head growth in early development of individuals with autism

…, SA Ravan, GR DeLong, RK Abramson, HH Wright… - Pediatric …, 2005 - Elsevier
Macrocephaly is one of the most consistent physical findings reported in autistic individuals.
Previous studies attempted to determine if macrocephaly is associated with risk for autism. …

Evaluation of copy number variations reveals novel candidate genes in autism spectrum disorder-associated pathways

…, I Konidari, PL Whitehead, HH Wright… - Human molecular …, 2012 - academic.oup.com
Autism spectrum disorders (ASDs) are highly heritable, yet relatively few associated genetic
loci have been replicated. Copy number variations (CNVs) have been implicated in autism; …

Association Analysis of Chromosome 15 GABAA Receptor Subunit Genes in Autistic Disorder

…, SA Ravan, RK Abramson, HH Wright… - Journal of …, 2001 - Taylor & Francis
Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the brain,
acting via the GABA A receptors. The GABA A receptors are comprised of several different …

[HTML][HTML] Investigation of autism and GABA receptor subunit genes in multiple ethnic groups

AL Collins, D Ma, PL Whitehead, ER Martin, HH Wright… - Neurogenetics, 2006 - Springer
Autism is a neurodevelopmental disorder of complex genetics, characterized by impairment
in social interaction and communication, as well as repetitive behavior. Multiple lines of …

Negative regulation of immunoglobulin E–dependent allergic responses by Lyn kinase

…, M Kovarova, Y Furumoto, JJ Ryan, HV Wright… - The Journal of …, 2004 - rupress.org
A role for Lyn kinase as a positive regulator of immunoglobulin (Ig)E-dependent allergy has
long been accepted. Contrary to this belief, Lyn kinase was found to have an important role …

Stat5 expression is critical for mast cell development and survival

…, P Mirmonsef, MN Mann, M Kashyap, HV Wright… - Blood, 2003 - ashpublications.org
Interleukin-3 (IL-3) and stem cell factor (SCF) are important mast cell growth and differentiation
factors. Since both cytokines activate the transcription factor signal transducer and …