User profiles for Hedley CA Emsley

Hedley Emsley

Consultant Neurologist & Professor of Clinical Neuroscience
Verified email at lthtr.nhs.uk
Cited by 10250

Acute ischaemic stroke and infection: recent and emerging concepts

HCA Emsley, SJ Hopkins - The Lancet Neurology, 2008 - thelancet.com
The relation between acute ischaemic stroke and infection is complex. Infection appears to
be an important trigger that precedes up to a third of ischaemic strokes and can bring about …

Evaluation of C-reactive protein measurement for assessing the risk and prognosis in ischemic stroke: a statement for health care professionals from the CRP Pooling …

…, E Ceccarelli, G Di Gianfilippo, C Donati, HCA Emsley… - Stroke, 2005 - Am Heart Assoc
Background and Purpose— Several studies have shown, in different populations, that
modest elevation of plasma C-reactive protein (CRP) in the range seen in apparently healthy …

Inflammation and infection in clinical stroke

HCA Emsley, PJ Tyrrell - Journal of Cerebral Blood Flow & …, 2002 - journals.sagepub.com
Stroke has enormous clinical, social, and economic implications, and demands a significant
effort from both basic and clinical science in the search for successful therapies. …

An early and sustained peripheral inflammatory response in acute ischaemic stroke: relationships with infection and atherosclerosis

HCA Emsley, CJ Smith, CM Gavin, RF Georgiou… - Journal of …, 2003 - Elsevier
Central nervous system and peripheral inflammation is important in the responses to ischaemic
stroke, and may also predispose to its development. We aimed to identify (1) the extent …

[HTML][HTML] HIV infection and stroke: current perspectives and future directions

LA Benjamin, A Bryer, HCA Emsley, S Khoo… - The Lancet …, 2012 - thelancet.com
HIV infection can result in stroke via several mechanisms, including opportunistic infection,
vasculopathy, cardioembolism, and coagulopathy. However, the occurrence of stroke and …

[HTML][HTML] Blood–brain barrier leakage is increased in Parkinson's disease

…, JH Naish, GJM Parker, HCA Emsley… - Frontiers in …, 2020 - frontiersin.org
Background Blood–brain barrier (BBB) disruption has been noted in animal models of
Parkinson’s disease (PD) and forms the basis of the vascular hypothesis of neurodegeneration, …

[HTML][HTML] The incidence of acute encephalitis syndrome in Western industrialised and tropical countries

F Jmor, HCA Emsley, M Fischer, T Solomon… - Virology Journal, 2008 - Springer
Background As part of efforts to control Japanese encephalitis (JE), the World Health
Organization is producing a set of standards for JE surveillance, which require the identification of …

HIV, antiretroviral treatment, hypertension, and stroke in Malawian adults: a case-control study

…, S Kampondeni, A Choko, M Hopkins, HCA Emsley… - Neurology, 2016 - AAN Enterprises
Objective: To investigate HIV, its treatment, and hypertension as stroke risk factors in
Malawian adults. Methods: We performed a case-control study of 222 adults with acute stroke, …

[HTML][HTML] A systematic review of glucose transport alterations in Alzheimer's disease

N Kyrtata, HCA Emsley, O Sparasci… - Frontiers in …, 2021 - frontiersin.org
Introduction: Alzheimer's disease (AD) is characterized by cerebral glucose hypometabolism.
Hypometabolism may be partly due to reduced glucose transport at the blood-brain barrier (…

International multicenter analysis of brain structure across clinical stages of Parkinson's disease

…, I Debove, MF Dirkx, J Druzgal, HCA Emsley… - Movement …, 2021 - Wiley Online Library
Background Brain structure abnormalities throughout the course of Parkinson's disease have
yet to be fully elucidated. Objective Using a multicenter approach and harmonized analysis …