Introduction Genetic polymorphisms in the promoter region of the tumour necrosis factor (TNF)
gene can regulate gene expression and have been associated with inflammatory and …

Background: Acute abdominal pain is the most common indication for surgical admission.
Nonspecific abdominal pain (NSAP) may account for up to 40% of cases. There has been no …

This review aims to change clinical practice and alert clinicians to consider that unrecognised
coeliac disease may present acutely with abdominal pain. Targeting patients who have …

… Sanders, MD, MRCP Iman AF Azmy, MD, FRCS San C. Kong, MD, MRCP Frederick KT
Lee, MD, FRCR Royal Hallamshire Hospital Sheffield Teaching Hospitals NHS Trust Sheffield, …

… Azmy’s comments and their interest in our article.We wish to clarify that our study design was
different than inferred by Sanders and Azmy. … Sanders and Azmy discuss the possibility of …

Out-of-programme (OOP) activities enable postgraduate trainees to undertake an experience
outside of their individual subspecialty training programmes. Activities vary but may include …

Although not mandatory, a period of formalized research leading to a higher degree is still
commonplace for doctors wishing to pursue a career in hospital medicine. This may be …

TO THE EDITOR: The recent study by Laurell et al. highlights the diagnostic problems of
acute abdominal pain Á a common emergency condition [1]. The investigators conclude that ‘‘…

How reliable are questionnaires about what skills medical students learnt in Sheffield, or
anywhere else? Sheffield used to have a system of social tutorial groups for studentsÐ perhaps …

People working in the acute setting share a spirit of comradeship and devotion to a purpose
that they believe in. This “esprit de corps” is not possible if you are not present on the ward …