User profiles for Indra N Guha
 | Neil GuhaProfessor of Hepatology , Univeristy of Nottingham Verified email at nottingham.ac.uk Cited by 7408 |
Accuracy of FibroScan controlled attenuation parameter and liver stiffness measurement in assessing steatosis and fibrosis in patients with nonalcoholic fatty liver …
Background & Aims We estimated the accuracy of FibroScan vibration-controlled transient
elastography controlled attenuation parameter (CAP) and liver stiffness measurement (LSMs) …
elastography controlled attenuation parameter (CAP) and liver stiffness measurement (LSMs) …
[HTML][HTML] FibroScan-AST (FAST) score for the non-invasive identification of patients with non-alcoholic steatohepatitis with significant activity and fibrosis: a prospective …
…, DA Sheridan, PJ Eddowes, IN Guha… - The lancet …, 2020 - thelancet.com
Background The burden of non-alcoholic fatty liver disease (NAFLD) is increasing globally,
and a major priority is to identify patients with non-alcoholic steatohepatitis (NASH) who are …
and a major priority is to identify patients with non-alcoholic steatohepatitis (NASH) who are …
[PDF][PDF] Validation of terminal peptide of procollagen III for the detection and assessment of nonalcoholic steatohepatitis in patients with nonalcoholic fatty liver disease
S Tanwar, PM Trembling, IN Guha, J Parkes… - …, 2013 - Wiley Online Library
Liver biopsy is the reference standard for the detection of nonalcoholic steatohepatitis (NASH)
within nonalcoholic fatty liver disease (NAFLD). The aim of this study was to identify a …
within nonalcoholic fatty liver disease (NAFLD). The aim of this study was to identify a …
A study of T1 relaxation time as a measure of liver fibrosis and the influence of confounding histological factors
…, A Austin, L Marciani, PA Gowland, IN Guha… - NMR in …, 2015 - Wiley Online Library
Liver biopsy is the standard test for the assessment of fibrosis in liver tissue of patients with
chronic liver disease. Recent studies have used a non‐invasive measure of T 1 relaxation …
chronic liver disease. Recent studies have used a non‐invasive measure of T 1 relaxation …
[PDF][PDF] Osteopontin is a novel downstream target of SOX9 with diagnostic implications for progression of liver fibrosis in humans
Osteopontin (OPN) is an important component of the extracellular matrix (ECM), which
promotes liver fibrosis and has been described as a biomarker for its severity. Previously, we …
promotes liver fibrosis and has been described as a biomarker for its severity. Previously, we …
Economic evaluation of a community-based diagnostic pathway to stratify adults for non-alcoholic fatty liver disease: a Markov model informed by a feasibility study
…, TR Card, G Gkountouras, V Berdunov, IN Guha… - BMJ open, 2017 - bmjopen.bmj.com
Objectives To assess the long-term cost-effectiveness of a risk stratification pathway, compared
with standard care, for detecting non-alcoholic fatty liver disease (NAFLD) in primary care…
with standard care, for detecting non-alcoholic fatty liver disease (NAFLD) in primary care…
Using non-invasive biomarkers to identify hepatic fibrosis in people with type 2 diabetes mellitus: the Edinburgh type 2 diabetes study
JR Morling, JA Fallowfield, IN Guha, LD Nee… - Journal of …, 2014 - Elsevier
Background & Aims It is difficult to determine the different stages of non-alcoholic fatty liver
disease without the use of invasive liver biopsy. In this study we investigated five non-invasive …
disease without the use of invasive liver biopsy. In this study we investigated five non-invasive …
Obesity is the most common risk factor for chronic liver disease: results from a risk stratification pathway using transient elastography
METHODS: We prospectively recruited patients from a primary care practice with hazardous
alcohol use and/or type 2 diabetes and/or obesity. Subjects were invited for a transient …
alcohol use and/or type 2 diabetes and/or obesity. Subjects were invited for a transient …
SOX 9 predicts progression toward cirrhosis in patients while its loss protects against liver fibrosis
Fibrosis and organ failure is a common endpoint for many chronic liver diseases. Much is
known about the upstream inflammatory mechanisms provoking fibrosis and downstream …
known about the upstream inflammatory mechanisms provoking fibrosis and downstream …
Performance characteristics of unsedated ultrathin video endoscopy in the assessment of the upper GI tract: systematic review and meta-analysis
Background and Aims Reports on the performance of unsedated ultrathin endoscopy via
the transnasal (uTNE) and transoral (uTOE) routes are conflicting. We aimed to estimate the …
the transnasal (uTNE) and transoral (uTOE) routes are conflicting. We aimed to estimate the …