Malignant pleural mesothelioma is an aggressive malignancy of the pleural surface,
predominantly caused by prior asbestos exposure. There is a global epidemic of malignant pleural …

Malignant pleural effusion (MPE) is a common but serious condition that is related with poor
quality of life, morbidity and mortality. Its incidence and associated healthcare costs are …

Malignant pleural effusions (MPE) are a common pathology, treated by respiratory physicians
and thoracic surgeons alike. In recent years, several well-designed randomized clinical …

The European Respiratory Society (ERS)/European Society of Thoracic Surgeons (ESTS)/European
Association for Cardio-Thoracic Surgery (EACTS)/European Society for …

Background Malignant pleural effusion affects more than 750,000 persons each year across
Europe and the United States. Pleurodesis with the administration of talc in hospitalized …

Importance For treatment of malignant pleural effusion, nonsteroidal anti-inflammatory drugs
(NSAIDs) are avoided because they may reduce pleurodesis efficacy. Smaller chest tubes …

Tumor necrosis factor (TNF)-α is present in the microenvironment of human tumors, including
malignant pleural effusion (MPE). Although the cytokine is produced in the pleural cavity by …

The glycoprotein osteopontin (OPN) possesses multiple functions in health and disease. To
this end, osteopontin has beneficial roles in wound healing, bone homeostasis, and …

Mast cells (MCs) have been identified in various tumors; however, the role of these cells in
tumorigenesis remains controversial. Here, we quantified MCs in human and murine …

BACKGROUND Definitive diagnosis of pleural disease (particularly malignancy) depends
upon histologic proof obtained via pleural biopsy or positive pleural fluid cytology. Image-…