Background The effect of decompressive craniectomy on clinical outcomes in patients with
refractory traumatic intracranial hypertension remains unclear. Methods From 2004 through …

Secondary insults can adversely influence outcome following severe traumatic brain injury.
Monitoring of cerebral extracellular chemistry with microdialysis has the potential for early …

Microdialysis enables the chemistry of the extracellular interstitial space to be monitored. Use
of this technique in patients with acute brain injury has increased our understanding of the …

Background Traumatic acute subdural hematomas frequently warrant surgical evacuation
by means of a craniotomy (bone flap replaced) or decompressive craniectomy (bone flap not …

Energy metabolism in the human brain is not fully understood. Classically, glucose is regarded
as the major energy substrate. However, lactate (conventionally a product of anaerobic …

Object Decompressive craniectomy is an advanced treatment option for intracranial
pressure (ICP) control in patients with traumatic brain injury. The purpose of this study was to …

Following traumatic brain injury (TBI), cascades of inflammatory processes occur. Laboratory
studies implicate the cytokines interleukin-1α (IL-1α) and IL-1β in the pathophysiology of …

Object Cerebrovascular pressure reactivity is the ability of cerebral vessels to respond to
changes in transmural pressure. A cerebrovascular pressure reactivity index (PRx) can be …

This study experimentally demonstrates infrared wavelength selective thermal emission
based on Tamm plasmon polaritons (TPPs). Unlike conventional TPP structures, which have a …

Background Two randomised trials assessing the effectiveness of decompressive craniectomy
(DC) following traumatic brain injury (TBI) were published in recent years: DECRA in …