Reactive arthritis is classically seen following infection with enteric pathogens such as Yersinia,
Salmonella, Campylobacter and Shigella. Inflammatory arthritis has also been described …

… JS Hill Gaston … JS Hill Gaston … Gaston had full access to all of the data in the study
and takes responsibility for the integrity of the data and the accuracy of the data analysis. …

Ankylosing spondylitis is a common form of inflammatory arthritis predominantly affecting
the spine and pelvis that occurs in approximately 5 out of 1,000 adults of European descent. …

The endoplasmic reticulum (ER) stress response detects malfunctions in cellular physiology,
and microbial pattern recognition receptors recognize external threats posed by infectious …

Background & Aims: The detection of phenotype-determining genes as opposed to disease
susceptibility genes requires precise phenotypic characterization of patients. Peripheral …

We have previously described critical and nonredundant roles for the phosphoinositide 3-kinase
p110δ during the activation and differentiation of naive T cells, and p110δ inhibitors are …

Onset of rheumatoid arthritis (RA) is widely believed to be preceded by exposure to some
environmental trigger such as bacterial infectious agents. The influence of bacteria on RA …

Dectin-1/CLEC7A is a pattern recognition receptor that recognizes β-1,3 glucans, and its
stimulation initiates signaling events characterized by the production of inflammatory cytokines …

It is clear that regulatory T cells (Treg) have an important role in preventing autoimmunity
and modulating responses to pathogens. Full characterization of Treg cell function in human …

The role of T lymphocytes in the pathology of rheumatoid arthritis (RA) is controversial. To
some extent this has resulted from contradictory data, but even where specific points of fact are …