In animals, acetylcholine dilates normal arteries and produces vasoconstriction in the
presence of hypercholesterolemia, hypertension, or atherosclerosis, reflecting endothelial cell …

In patients with hypertension, a pattern of left ventricular hypertrophy on the electrocardiogram
is associated with a risk of sudden death in excess of the risk attributable to hypertension …

OBJECTIVE: To evaluate the role of haemostatic and haemodynamic variables in left atrial
thrombosis in non-rheumatic atrial fibrillation. DESIGN: Case-control study. SUBJECTS: One …

… Pfeffer MA, Pfeffer JM: Left ventricular hypertrophy and pressure generating capacity in
ageing genetically hypertensive rats. J Cardiovasc Pharmacol 1985;7:S41S47. …

BACKGROUND Healthy arteries exhibit endothelium-dependent dilation in response to both
local acetylcholine and increased blood flow. In humans, clinically overt coronary artery …

Aims To quantify the determinants of primary percutaneous coronary intervention (PCI)
performance in England and Wales between 2004 and 2007. Methods and results All 8653 …

This study investigated the vasodilator function of endothelium that regenerated after
balloon angioplasty and the relation of this function to the extent of vascular injury and to …

Intracoronary acetylcholine produces endothelium-dependent dilation of normal coronary
arteries and paradoxical constriction of atherosclerotic vessels. Regional differences in …

Acute coronary syndromes presenting with ST elevation are usually treated with emergency
reperfusion/revascularisation therapy. In contrast current evidence and national guidelines …

BACKGROUND: Primary percutaneous coronary intervention (PCI) is the preferred treatment
for ST-segment elevation myocardial infarction (STEMI) provided it can be delivered within …