User profiles for Jack Satsangi
 | Jack SatsangiProfessor of Gastroenterology Verified email at ed.ac.uk Cited by 70005 |
Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease
…, RK Russell, JD Sanderson, M Sans, J Satsangi… - Nature, 2012 - nature.com
Crohn’s disease and ulcerative colitis, the two common forms of inflammatory bowel disease
(IBD), affect over 2.5 million people of European ancestry, with rising prevalence in other …
(IBD), affect over 2.5 million people of European ancestry, with rising prevalence in other …
Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: report of a Working Party of the 2005 Montreal World Congress …
The discovery of a series of genetic and serological markers associated with disease
susceptibility and phenotype in inflammatory bowel disease has led to the prospect of an …
susceptibility and phenotype in inflammatory bowel disease has led to the prospect of an …
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
Several risk factors for Crohn's disease have been identified in recent genome-wide association
studies. To advance gene discovery further, we combined data from three studies on …
studies. To advance gene discovery further, we combined data from three studies on …
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
We undertook a meta-analysis of six Crohn's disease genome-wide association studies (GWAS)
comprising 6,333 affected individuals (cases) and 15,056 controls and followed up the …
comprising 6,333 affected individuals (cases) and 15,056 controls and followed up the …
Guidelines for the management of inflammatory bowel disease in adults
The management of inflammatory bowel disease represents a key component of clinical
practice for members of the British Society of Gastroenterology (BSG). There has been …
practice for members of the British Society of Gastroenterology (BSG). There has been …
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
Genome-wide association studies and candidate gene studies in ulcerative colitis have
identified 18 susceptibility loci. We conducted a meta-analysis of six ulcerative colitis genome-…
identified 18 susceptibility loci. We conducted a meta-analysis of six ulcerative colitis genome-…
Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility
…, A Forbes, J Sanderson, DP Jewell, J Satsangi… - Nature …, 2007 - nature.com
A genome-wide association scan in individuals with Crohn's disease by the Wellcome Trust
Case Control Consortium detected strong association at four novel loci. We tested 37 SNPs …
Case Control Consortium detected strong association at four novel loci. We tested 37 SNPs …
Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease
Genetic association studies have identified 215 risk loci for inflammatory bowel disease 1 ,
2 , 3 , 4 , 5 , 6 , 7 , 8 , thereby uncovering fundamental aspects of its molecular biology. We …
2 , 3 , 4 , 5 , 6 , 7 , 8 , thereby uncovering fundamental aspects of its molecular biology. We …
Definition of phenotypic characteristics of childhood-onset inflammatory bowel disease
…, LT Weaver, WM Bisset, G Mahdi, ID Arnott, J Satsangi… - Gastroenterology, 2008 - Elsevier
Background & Aims: Childhood-onset inflammatory bowel disease (IBD) might be etiologically
different from adult-onset IBD. We analyzed disease phenotypes and progression of …
different from adult-onset IBD. We analyzed disease phenotypes and progression of …
Two stage genome–wide search in inflammatory bowel disease provides evidence for susceptibility loci on chromosomes 3, 7 and 12
Crohn's disease (CD) and ulcerative colitis (UC), the chronic inflammatory bowel diseases (CIBD),
are common causes of gastro-intestinal disease in the Western world, with a …
are common causes of gastro-intestinal disease in the Western world, with a …