Safety and efficacy of ozanimod versus interferon beta-1a in relapsing multiple sclerosis (SUNBEAM): a multicentre, randomised, minimum 12-month, phase 3 trial

…, EK Havrdová, BAC Cree, JK Sheffield… - The Lancet …, 2019 - thelancet.com
Background Ozanimod, a sphingosine 1-phosphate receptor modulator, selectively binds to
receptor subtypes 1 and 5 with high affinity. The RADIANCE phase 2 study showed that …

Safety and efficacy of ozanimod versus interferon beta-1a in relapsing multiple sclerosis (RADIANCE): a multicentre, randomised, 24-month, phase 3 trial

…, EK Havrdová, BAC Cree, JK Sheffield… - The Lancet …, 2019 - thelancet.com
Background Ozanimod is a sphingosine 1-phosphate receptor modulator, which selectively
binds to sphingosine 1-phosphate receptor subtypes 1 and 5 with high affinity. In the …

A paradigmatic and methodological examination of knowledge management research: 2000 to 2004

Z Guo, J Sheffield - Decision Support Systems, 2008 - Elsevier
Knowledge management (KM) research has been evolving for more than a decade, yet little
is known about KM theoretical perspectives, research paradigms, and research methods. …

Long-term safety and efficacy of ozanimod in relapsing multiple sclerosis: up to 5 years of follow-up in the DAYBREAK open-label extension trial

…, EK Havrdová, JK Sheffield… - Multiple Sclerosis …, 2022 - journals.sagepub.com
Background: Ozanimod, an oral sphingosine 1-phosphate receptor 1 and 5 modulator, is
approved in multiple countries for treatment of relapsing forms of MS. Objective: To …

Intelligence‐led policing and change in state law enforcement agencies

LM Schaible, J Sheffield - Policing: An International Journal of Police …, 2012 - emerald.com
The events of September 11, 2001 forever changed policing with state and local law
enforcement now playing a central role. In this new role many agencies have begun to re‐assess …

Inquiry in health knowledge management

J Sheffield - Journal of Knowledge Management, 2008 - emerald.com
Purpose – The purpose of this paper is to reduce ambiguity in diverse approaches to health
knowledge management by surfacing key issues, perspectives and philosophical …

[HTML][HTML] Personalized brain stimulation for effective neurointervention across participants

…, TL Reed, V Nguyen, JG Sheffield… - PLoS computational …, 2021 - journals.plos.org
Accumulating evidence from human-based research has highlighted that the prevalent one-size-fits-all
approach for neural and behavioral interventions is inefficient. This approach can …

Motor overflow and mirror dystonia

O Sitburana, LJC Wu, JK Sheffield, A Davidson… - Parkinsonism & Related …, 2009 - Elsevier
Motor overflow is an unintentional muscle contraction which accompanies, but is anatomically
distinct from the primary dystonic movement. This phenomenological nosology has not …

[HTML][HTML] Effect of ozanimod on symbol digit modalities test performance in relapsing MS

…, G Comi, DL Arnold, HP Hartung, JK Sheffield… - Multiple Sclerosis and …, 2021 - Elsevier
Background Cognitive dysfunction, including slowed cognitive processing speed (CPS), is
one of the most disabling symptoms of multiple sclerosis (MS). The Symbol Digit Modalities …

Comparative safety and efficacy of ozanimod versus fingolimod for relapsing multiple sclerosis

…, C Pelletier, D Kao, JK Sheffield… - Journal of …, 2020 - becarispublishing.com
Aim: Ozanimod and fingolimod are sphingosine 1-phosphate receptor–modulating therapies
for relapsing multiple sclerosis. Patients & methods: Comparative effectiveness was …