Asthma is characterized by airway inflammation and remodeling and CXCL8 is a CXC
chemokine that drives steroid-resistant neutrophilic airway inflammation. We have shown that …

Those experiencing homelessness in Canada are impacted inequitably by COVID-19 due to
their increased exposure, vulnerability of environment and medical comorbidities, and their …

Background and purpose: Endothelin‐1 (ET‐1) is implicated in airway inflammation in asthma,
but the mechanisms of its effects are poorly understood. We studied the effect of ET‐1 on …

Background Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease of
the lungs that is currently the fourth leading cause of death worldwide. Genetic factors …

Background: Educators utilize real patients, simulated patients (SP), and student role play (RP)
in communication skills training (CST) in medical curricula. The chosen modality may …

Purpose People experiencing homelessness (PEH) are at increased risk of respiratory infections
and associated morbidity and mortality. To characterize optimal intervention strategies, …

Monocyte chemotactic protein-1 (MCP-1) is a member of the CC family of cytokines. It has
monocyte and lymphocyte chemotactic activity and stimulates histamine release from …

Objectives To report changes in practice brought about by COVID‐19 and the implementation
of new guidelines, and to explore factors relating to unscheduled re‐presentations for …

Background Mesenchymal fibroblasts are ubiquitous cells that maintain the extracellular
matrix of organs. Within the lung, airway and parenchymal fibroblasts are crucial for lung …

The airway epithelium forms the interface between the inhaled environment and the lung.
The airway epithelium is dysfunctional in asthma and epigenetic mechanisms are considered …