User profiles for Jan Münch
Jan MünchUlm University Verified email at uni-ulm.de Cited by 15493 |
[PDF][PDF] SARS-CoV-2 variants B. 1.351 and P. 1 escape from neutralizing antibodies
The global spread of SARS-CoV-2/COVID-19 is devastating health systems and economies
worldwide. Recombinant or vaccine-induced neutralizing antibodies are used to combat the …
worldwide. Recombinant or vaccine-induced neutralizing antibodies are used to combat the …
[HTML][HTML] SARS-CoV-2 infects and replicates in cells of the human endocrine and exocrine pancreas
Infection-related diabetes can arise as a result of virus-associated β-cell destruction.
Clinical data suggest that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), …
Clinical data suggest that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), …
[HTML][HTML] Semen-derived amyloid fibrils drastically enhance HIV infection
J Münch, E Rücker, L Ständker, K Adermann… - Cell, 2007 - cell.com
Sexual intercourse is the major route of HIV transmission. To identify endogenous factors
that affect the efficiency of sexual viral transmission, we screened a complex peptide/protein …
that affect the efficiency of sexual viral transmission, we screened a complex peptide/protein …
Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation
Many globular and natively disordered proteins can convert into amyloid fibrils. These fibrils
are associated with numerous pathologies 1 as well as with normal cellular functions 2 , 3 , …
are associated with numerous pathologies 1 as well as with normal cellular functions 2 , 3 , …
[HTML][HTML] Detection of SARS-CoV-2 in human breastmilk
It remains unclear whether severe acute respiratory syndrome corona virus 2 (SARSCoV2)
can be shed into breastmilk and transmitted to a child through breastfeeding. Recent …
can be shed into breastmilk and transmitted to a child through breastfeeding. Recent …
Virucidal efficacy of different oral rinses against severe acute respiratory syndrome coronavirus 2
The ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic
creates a significant threat to global health. Recent studies suggested the significance of throat …
creates a significant threat to global health. Recent studies suggested the significance of throat …
[HTML][HTML] Nef-mediated suppression of T cell activation was lost in a lentiviral lineage that gave rise to HIV-1
M Schindler, J Münch, O Kutsch, H Li, ML Santiago… - Cell, 2006 - cell.com
High-level immune activation and T cell apoptosis represent a hallmark of HIV-1 infection
that is absent from nonpathogenic SIV infections in natural primate hosts. The mechanisms …
that is absent from nonpathogenic SIV infections in natural primate hosts. The mechanisms …
[PDF][PDF] Tetherin-driven adaptation of Vpu and Nef function and the evolution of pandemic and nonpandemic HIV-1 strains
…, M Schindler, A Specht, WN Landford, J Münch… - Cell host & …, 2009 - cell.com
Vpu proteins of pandemic HIV-1 M strains degrade the viral receptor CD4 and antagonize
human tetherin to promote viral release and replication. We show that Vpus from SIVgsn, …
human tetherin to promote viral release and replication. We show that Vpus from SIVgsn, …
[HTML][HTML] Immune responses against SARS-CoV-2 variants after heterologous and homologous ChAdOx1 nCoV-19/BNT162b2 vaccination
…, A Janssen, G Ssebyatika, G Bernhardt, J Münch… - Nature medicine, 2021 - nature.com
Currently approved viral vector-based and mRNA-based vaccine approaches against
coronavirus disease 2019 (COVID-19) consider only homologous prime-boost vaccination. After …
coronavirus disease 2019 (COVID-19) consider only homologous prime-boost vaccination. After …
[HTML][HTML] TRIM proteins regulate autophagy and can target autophagic substrates by direct recognition
Autophagy, a homeostatic process whereby eukaryotic cells target cytoplasmic cargo for
degradation, plays a broad role in health and disease states. Here we screened the TRIM family …
degradation, plays a broad role in health and disease states. Here we screened the TRIM family …